Results 11 to 20 of about 386,189 (210)

Circulating microRNA expression signatures accurately discriminate myalgic encephalomyelitis from fibromyalgia and comorbid conditions

Scientific Reports, 2023
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), and fibromyalgia (FM) are two chronic complex diseases with overlapping symptoms affecting multiple systems and organs over time.
Evguenia Nepotchatykh, Iurie Caraus, Wesam Elremaly, Corinne Leveau, Mohamed Elbakry, Christian Godbout, Bita Rostami-Afshari, Diana Petre, Nasrin Khatami, Anita Franco, Alain Moreau   +10 more
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Value of MRI and ultrasound for prediction of therapeutic response and erosive progression in patients with early rheumatoid arthritis managed by an aggressive treat-to-target strategy

RMD Open, 2021
Objectives To investigate if inflammation detected by MRI or ultrasound at rheumatoid arthritis (RA) onset is predictive of erosive progression or poor response to methotrexate monotherapy, and to investigate if subclinical inflammation in remission is ...
, Désirée van der Heijde, Tore K Kvien, Gunnstein Bakland, Lena Bugge Nordberg, Siri Lillegraven, Anna-Birgitte Aga, Joseph Sexton, Espen A Haavardsholm, Erik Rødevand, Hilde Berner Hammer, Ulf Sundin, Nina Paulshus Sundlisater, Hallvard Fremstad, Tor Magne Madland, Åse Stavland Lexberg, Hilde Haukeland, Christian Høili, Hilde Stray, Anne Noraas Bendvold, Inger W Hansen   +20 more
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Optimal treatment strategies for musculoskeletal diseases [PDF]

, 2013
This paper presents a model which aims to find an optimal treatment time for patients with musculoskeletal diseases. The stochastic dynamic programming model presented is based on minimizing expected costs given a stochastic processes for cure with ...
Haugen, Kjetil K.
core   +1 more source

Insights into the underlying pathogenesis and therapeutic potential of endoplasmic reticulum stress in degenerative musculoskeletal diseases

Military Medical Research, 2023
Degenerative musculoskeletal diseases are structural and functional failures of the musculoskeletal system, including osteoarthritis, osteoporosis, intervertebral disc degeneration (IVDD), and sarcopenia.
Ze-Qin Wen, Jun Lin, Wen-Qing Xie, Yun-Han Shan, Ge-Hua Zhen, Yu-Sheng Li   +5 more
doaj   +1 more source

Endogenous musculoskeletal tissue engineering - a focused perspective [PDF]

, 2012
Two major difficulties facing widespread clinical implementation of existing Tissue Engineering (TE) strategies for the treatment of musculoskeletal disorders are (1) the cost, space and time required for ex vivo culture of a patient’s autologous cells ...
Adam, Clayton
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Lived experiences of informal caregivers of people with chronic musculoskeletal pain: a systematic review and meta-ethnography [PDF]

, 2021
BACKGROUND: People with chronic pain often seek support from friends and family for everyday tasks. These individuals are termed informal caregivers. There remains uncertainty regarding the lived experiences of these people who care for individuals with ...
Bowlby J., Bronfenbrenner U, GBD, Major CH, Mease P., Merskey H, Sofaer-Bennett B   +6 more
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Association of Painful musculoskeletal conditions and migraine headache with mental and sleep disorders among adults with disabilities, Spain, 2007-2008. [PDF]

, 2014
Introduction: The aim of the study was to determine the prevalence of musculoskeletal painful conditions and migraine/headache in a population with disabilities, and their association with anxiety, depression and sleep disorders.
Agüera, Agüera-Ortiz, Asghari, Astin, Bravo, Breivik, Campbell, Evans, Fernández-de-Las-Peñas, Fernández-de-Las-Peñas, Fillingim, Heiberg, Hirsh, Jones, Keogh, Leveille, Magarolas, Nihayah, Ohayon, Pinto-Meza, Racine, Scott, Smith, Stubbs, Tarsuslu, Thompson, Valderrama-Gama, Von Korff   +27 more
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Modulation of Microglia by Voluntary Exercise or CSF1R Inhibition Prevents Age-Related Loss of Functional Motor Units

Cell Reports, 2019
Summary: Age-related loss of skeletal muscle innervation by motor neurons leads to impaired neuromuscular function and is a well-established clinical phenomenon. However, the underlying pathogenesis remains unclear. Studying mice, we find that the number
Elisa Giorgetti, Moh Panesar, Yunyu Zhang, Stefanie Joller, Marie Ronco, Michael Obrecht, Christian Lambert, Nathalie Accart, Nicolau Beckmann, Arno Doelemeyer, Ludovic Perrot, Isabelle Fruh, Matthias Mueller, Eliane Pierrel, Serge Summermatter, Michael Bidinosti, Derya R. Shimshek, Sophie Brachat, Mark Nash   +18 more
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Incidence of Unrecognized Incidental Durotomy during Surgery for Malignant Spinal Tumor

Spine Surgery and Related Research, 2020
Introduction: Cerebral spinal fluid leak from durotomy is a well-known risk with spinal surgeries. The aim of this study is to identify the incidence of unrecognized incidental durotomy during posterior surgery for spinal metastases and its risk factors.
Takuma Koyama, Shurei Sugita, Takahiro Hozumi, Masanori Fujiwara, Kiyofumi Yamakawa, Tomotake Okuma, Takahiro Goto   +6 more
doaj   +1 more source

Angiogenic T Cells: Potential Biomarkers for the Early Diagnosis of Interstitial Lung Disease in Autoimmune Diseases?

Biomedicines, 2022
(1) Background: We explored, for the first time, the contribution of angiogenic T cells (TAng) in interstitial lung disease associated to autoimmune disease (AD-ILD+) as potential biomarkers of the disease, evaluating their role in the underlying ...
Verónica Pulito-Cueto, Sara Remuzgo-Martínez, Fernanda Genre, Belén Atienza-Mateo, Víctor M. Mora-Cuesta, David Iturbe-Fernández, Leticia Lera-Gómez, Javier Rodriguez-Carrio, Diana Prieto-Peña, Virginia Portilla, Ricardo Blanco, Alfonso Corrales, Oreste Gualillo, José M. Cifrián, Raquel López-Mejías, Miguel A. González-Gay   +15 more
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