Results 131 to 140 of about 3,411,554 (367)

Skeletal Muscle HSF1 Alleviates Age‐Associated Sarcopenia and Mitochondrial Function Decline via SIRT3‐PGC1α Axis

Advanced Science, EarlyView.
Aged HSF1 muscle‐specific knockout mice show deteriorated muscle atrophy and metabolic dysfunction, while active HSF1 overexpression improves muscle function via activating SIRT3 to deacetylate both PGC1α1 and PGC1α4, which boosts mitochondrial function and muscle hypertrophy in a fiber‐type specific manner, and induces FNDC5/Irisin for tissue ...
Jun Zhang, Min Hu, Xia Wu, Mingwei Guo, Ying Ma, Jin Qiu, Siqi Wang, Yuxiang Cao, Yinzhao Zhong, Fangfang Chen, Yiwen Wang, Wei Wei, Yan Lu, Yong Zhang, Junjie Xiao, Zhenji Gan, Cheng Hu, Xinran Ma, Lingyan Xu   +18 more
wiley   +1 more source

Efficacy of adding manual therapy to hip and knee exercises in patients with patellofemoral pain syndrome: a double-blinded randomized controlled clinical trial

Scientific Reports
Patellofemoral pain syndrome (PFPS) is the most common knee problem that affects the knee in adulthood. It is more common in females twice than in males. It has a multifactorial etiology.
Nadia Abdo, Enas Fawzy Youssef, Mona Mohamed Ibrahim   +2 more
doaj   +1 more source

Multi‐Omics Reveal the Dysregulated Gut‐Joint Axis in Knee Synovitis: Data from Two Osteoarthritis Studies in China

Advanced Science, EarlyView.
The “gut‐joint axis” in knee synovitis is uncovered. Integrated multi‐omics studies are conducted in two independent osteoarthritis cohorts. Synovitis is characterized an increased F/B ratio, as well as alterations of 3‐HIA, geranic acid, and TWEAK. Upregulated TWEAK receptor is found in high‐grade synovitis, and inversely correlated with lower TWEAK ...
Xiaoshuai Wang, Yi Liu, Ziying Sun, Jia Li, Zhihao Lu, Jiayuan Huang, Shixian Hu, Peihua Cao, Xiaolong Cao, Shangru Li, Jianzhao Ruan, Jinhui Liu, Jingyu Xie, Haitao Sun, Tianyu Chen, Shengfa Li, Zhaohua Zhu, Zhibo Wen, Rocky S. Tuan, David John Hunter, Zhong Alan Li, Dongquan Shi, Changhai Ding   +22 more
wiley   +1 more source

The Association of Anterior Pelvic Tilt Angle and Clinical Knee Outcomes among Patients with Patellofemoral Pain: A Cross-Sectional Study. [PDF]

Journal of Bioscience and Applied Research
Background: Patellofemoral Pain (PFP) is a frequent musculoskeletal disorder that affects young active subjects and the public. A significant contributing component to the etiology of PFP is an alteration of the lower limb kinetic chain.
Labib Ghali, Enas Youssef, Tarek Diab, Marihan Aziz   +3 more
doaj   +1 more source

Prevalence of Musculoskeletal Disorders and Ergonomic Risk Factors among Firefighters

, 2023
Hamza Farooq, Montakarn Chaikumarn
openalex   +2 more sources

Ergonomic risk and preventive measures of musculoskeletal disorders in the dentistry environment: an umbrella review

PeerJ, 2018
Introduction Dental practitioners are exposed to different occupational hazards during the course of their professional activity, such as physical, chemical, biological, ergonomic factors.
S. De Sio, Veronica Traversini, F. Rinaldo, V. Colasanti, G. Buomprisco, R. Perri, Federica Mormone, G. La Torre, F. Guerra   +8 more
semanticscholar   +1 more source

Increased Blood Flow and Tendon Swelling Precedes Vascular Expansion and Tissue Matrix Changes In Early Human Tendinopathy: A Potential Window for Superior Treatment Response

Advanced Science, EarlyView.
Human participants with early‐ or chronic‐stage tendinopathy and healthy controls are investigated using ultrasound Doppler, 3T and 7T MRI, and tendon biopsies. Tendon swelling and hyperperfusion are evident early, while vascular growth and extracellular matrix changes are most pronounced in chronic tendinopathy. Early intervention may provide superior
Max F. R. Merkel, Nikolaj M. Malmgaard‐Clausen, Marius Lendal, Hartwig R. Siebner, René B. Svensson, Stephanie G. Dakin, Marcus Krüger, Luisa Schmidt, Jakob Agergaard, Ching‐Yan Chloé Yeung, S. Peter Magnusson, Michael Kjaer   +11 more
wiley   +1 more source

XML The Relationship Between the Ergonomic Situation of the Workstations and Musculoskeletal Disorders With the Quality of Work Life And Demographic Variables in the Administrative Staff of the Tehran Municipality [PDF]

, 2017
Pezhvak Ghasemzade, Shahnaz Tabatabaei, Amir Kavousi, Mahnaz Sareme   +3 more
openalex   +1 more source

Modulating Integrin and Growth Factor Signaling With Peptides: Strategies to Synergistically Enhance Bone Tissue Regeneration

Advanced Science, EarlyView.
It has been demonstrated that, in the bone extracellular matrix (ECM), integrins and growth factor receptors (GFRs) engage in synergistic signaling to guide bone healing and regeneration. This review provides a comprehensive overview of current strategies using ECM‐derived peptides to recreate the cellular microenvironment and harness synergistic ...
Lluís Oliver‐Cervelló, Elisabetta Ada Cavalcanti‐Adam, Carlos Mas‐Moruno   +2 more
wiley   +1 more source

Computer users at risk: Health disorders associated with prolonged computer use [PDF]

By keeping in view the ISO standards which emphasize the assessment of use of a product, this research aims to assess the prolonged use of computers and their effects on human health. The objective of this study was to investigate the association between
Abida Ellahi, Fouzia Akram, M. Shahid Khalil   +2 more
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