Results 151 to 160 of about 205,535 (299)
Animal Models and Experimental Medicine, EarlyView.ErZhi formula (EZF) is composed of Ligustri Lucidi Fructus (LLF) and Ecliptae herba (EH). Ovariectomized (OVX) and sham rats received 12‐week intragastric treatment with EZF, alendronate, and vehicle saline. Gastrocnemius tissues were harvested to systematically evaluate pharmacodynamic changes in skeletal muscle morphology, mitochondrial ...
Yuqing Pang +7 more
wiley +1 more source
The burden placed on society as a result of musculoskeletal disorders is substantial, requiring effective management especially in an occupational context. Recent occupational health guidelines recommend addressing potentially detrimental psychosocial
Bartys, Serena
core
Multimorbidity and Associations with Cognition and Alzheimer's Disease Biomarkers
Annals of Neurology, EarlyView.Objective Multimorbidity, the coexistence of 2 or more chronic conditions, has been linked to cognitive aging and Alzheimer's disease (AD) and AD‐related dementias, yet the mechanisms remain unclear. We aimed to examine the associations of multimorbidity with cognition and biomarkers across multiple mechanistic pathways.
Xiaqing Jiang +45 more
wiley +1 more source
BMC GeriatricsBackground Cellular senescence is a hallmark of aging, characterized by the secretion of proinflammatory factors known as the senescence-associated secretory phenotype (SASP). While physical exercise is proposed as a potential modulator of cellular aging,
Eleuterio A. Sánchez-Romero +5 more
doaj +1 more source
Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles
Advanced NanoBiomed Research, EarlyView.This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley +1 more source
Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis
Advanced NanoBiomed Research, EarlyView.Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia +10 more
wiley +1 more source
A Study on Musculoskeletal Disorders and Personal and Occupational Risk Factors among Surgeons
علوم بهداشتی ایران, 2013 Background and purpose: Surgery is a high risk profession owing to musculoskeletal disorders (MSDs). Fine and precise operations cause surgeons to adopt prolonged fixed posture.
A Tirgar, Sh Khallaghi, M Taghipour
doaj
Advanced Physics Research, EarlyView.A physics‐grounded framework based on decoherence timescales (τ_dec vs τ_func), Markovian validity, and falsifiability criteria is applied across molecular systems to distinguish where quantum effects are necessary, marginal, or irrelevant. The analysis integrates quantum chemistry, biological quantum mechanisms, and quantum computing under a unified ...
Sarfaraz K. Niazi
wiley +1 more source
The Anatomical Record, EarlyView.Abstract Studies investigating paleopathologies in sauropods remain scarce despite their relative abundance in the fossil record. In this study we report new occurrence of paleopathological features, corresponding to a neoplasm found in a middle caudal vertebra (MCT.R.2120) of an advanced titanosaur from the Presidente Prudente Formation (Bauru Basin ...
Maria Luiza Peres Bertolossi +5 more
wiley +1 more source
Special Issue “Role of Exercises in Musculoskeletal Disorders—6th Edition”
The sixth edition of the Special Issue entitled “Role of Exercise in Musculoskeletal Disorders” has been collated, substantially advancing the conversation on the effectiveness and practicality of exercise-based interventions for individuals ...
Giuseppe Musumeci
core +1 more source