Results 151 to 160 of about 3,411,554 (367)

Senescent Synovial Intimal Fibroblasts Aggravate Osteoarthritis by Regulating Macrophage Polarization and Chondrocyte Phenotype Through ANGPTL4‐α5β1 Axis

open access: yesAdvanced Science, EarlyView.
Senescent synovial intimal fibroblasts (SIF) are identified as key drivers of osteoarthritis. They promote M1 macrophage polarization and cartilage degeneration via the ANGPTL4–α5β1 axis, regulated by transcription factors EGR1 and ATF3. Pharmacological inhibition of this pathway alleviates disease, revealing SIF senescence as a promising therapeutic ...
Muhai Deng   +7 more
wiley   +1 more source

Prospective associations between 24-h device-measured occupational and leisure-time physical activity and register-based musculoskeletal-related primary healthcare utilization among Danish workers

open access: yesScientific Reports
Musculoskeletal pain is a leading cause of seeking care and imposes an immense economic burden to the healthcare systems. The guidelines recommend physical activity for managing musculoskeletal pain but do not differentiate between occupational and ...
Stavros Kyriakidis   +5 more
doaj   +1 more source

The Best Current Research on Patellar Tendinopathy: A Review of Published Meta-Analyses

open access: yesSports
Patellar tendinopathy is a frequent overuse injury in sports that can cause significant pain and disability. It requires evidence-based guidelines on effective prevention and management. However, optimal treatments remain uncertain.
Rafael Llombart   +3 more
doaj   +1 more source

Achieving workplace inclusiveness by using ergonomics risk assessment [PDF]

open access: yes, 2013
Traditional manufacturing work practices do not consider human variability issues during the design process. However, most manual assembly activities demand high levels of repetition and speed without compromising product quality and work productivity ...
Case, Keith   +3 more
core  

A Wearable System Featuring Biomimetic Spatially Distributed Iontronic Sensing Array for Dynamic Monitoring of Deep Tissue Modulus

open access: yesAdvanced Science, EarlyView.
A fully wearable system enables real‐time, dynamic, and accurate monitoring of Young's modulus in multilayer tissues containing deep muscle. It demonstrates high accuracy and robustness across simulations, benchtop validations, and human testing. It quantifies edema severity and tracks muscle stiffness during rest, loaded elbow flexion, rope skipping ...
Zhenning Wang   +12 more
wiley   +1 more source

Musculoskeletal symptoms in SARS-CoV-2 (COVID-19) patients

open access: yesJournal of Orthopaedic Surgery and Research, 2020
Lucio Cipollaro   +4 more
doaj   +1 more source

Identifying patients with shoulder impingement syndrome who improve with scapular training: a clinical prediction study

open access: yesPhysiotherapy Quarterly
Introduction There is a preponderance of evidence that scapular training improves scapular muscle performance and decreases the clinical symptoms related to subacromial impingement syndrome (SAIS).
Ahmed M. El Melhat   +4 more
doaj   +1 more source

Spatial Transcriptomics of TMJ Reveals a Remodeling Fibroblast‐Immune Microenvironment Driving Arthritis Pain

open access: yesAdvanced Science, EarlyView.
Spatial transcriptomics reveals a remodeled fibroblast‐immune microenvironment in the temporomandibular joint (TMJ) during arthritis. By combining seqFISH with genetic mouse models, this study uncovers TMJ spatial cell atalas, macrophage‐fibroblast crosstalk, and cytokine signaling pathways driving TMJ inflammation and pain.
Ziying Lin   +10 more
wiley   +1 more source

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