Results 71 to 80 of about 177,722 (252)

The Association of Anterior Pelvic Tilt Angle and Clinical Knee Outcomes among Patients with Patellofemoral Pain: A Cross-Sectional Study. [PDF]

Journal of Bioscience and Applied Research
Background: Patellofemoral Pain (PFP) is a frequent musculoskeletal disorder that affects young active subjects and the public. A significant contributing component to the etiology of PFP is an alteration of the lower limb kinetic chain.
Labib Ghali, Enas Youssef, Tarek Diab, Marihan Aziz   +3 more
doaj   +1 more source

A Multidirectional Textile Interface for Remote Control Using Dynamic Area‐Based Capacitance Modulation

Advanced Robotics Research, EarlyView.
Here, we present a textile, wearable capacitive interface enabling multidirectional remote control by dynamically modulating electrode overlap and spacing via a freely gliding upper electrode. A forearm‐mounted prototype drives robotic and media tasks with 12–15 ms latency, maintains < 0.8% drift after 500 cycles, and remains stably functional at 90 ...
Cagatay Gumus, Fulya Yenilmez, Kadir Ozlem, Hakan Kestir, Eren Tasdemir, Berkant Bakisli, Gökhan Ince, Ozgur Atalay, Asli Tuncay Atalay   +8 more
wiley   +1 more source

Engineered Exosomal miR‐146a‐5p Reprograms BMSC Fate and Restores Mitochondrial Homeostasis in Glucocorticoid‐Induced Osteonecrosis of Femoral Head

Advanced Science, EarlyView.
Exosomal miR‐146a‐5p is identified as a pivotal regulator in steroid‐induced osteonecrosis. Its reduction activates NF‐κB signaling, compromises mitophagy, and disrupts mitochondrial bioenergetics, resulting in autophagic disequilibrium. Engineered exosomes delivering miR‐146a‐5p reinstate mitochondrial function, augment oxidative phosphorylation and ...
Zehui Lv, Xuejie Cai, Yiming Xu, Xingdong Yang, Ruoying Wang, Han Wang, Yixin Bian, Jiawei Xu, Jiao Lu, Lulu Liu, Yingjie Wang, Jibin Song, Bin Feng, Xisheng Weng   +13 more
wiley   +1 more source

Targeting Dnmt3a/m5C/RelA Axis Attenuates Microglia Inflammatory Response and Improves Postoperative Recovery in Chronic Compressive Cervical Spinal Cord Injury

Advanced Science, EarlyView.
A pro‐inflammatory microglial subset persists after decompression in chronic compressive cervical spinal cord injury and shows enhanced Dnmt3a‐driven m5C signaling. By stabilizing RelA mRNA, this axis sustains NF‐κB activation and postoperative neuroinflammation.
Tianyu Qin, Yuan Jiang, Yongheng Xie, Huanwei Qu, Wenbin Yan, Jingle Chen, Yining Chen, Huayi Li, Naibo Feng, Jiajun Wu, Chao Zhang, Zhengqi Huang, Ming Shi, Zhihuai Deng, Guozhi Xiao, Houqing Long   +15 more
wiley   +1 more source

Quadriceps tendon autograft with patellar bone block and semitendinosus augmentation demonstrates predictable midterm outcomes for patellar tendon disruption following primary total knee arthroplasty

Journal of Experimental Orthopaedics
Purpose Patellar tendon (PT) disruption following primary total knee arthroplasty (TKA) is an uncommon but devastating complication, with current available surgical options reporting fair to poor long‐term results.
Ashok Rajgopal, Saksham Tripathi, Manish Kumar Singh, Kalpana Aggarwal   +3 more
doaj   +1 more source

THBS1+ Macrophages Exacerbate Modic Changes via SDC4‐Dependent Activation of NLRP3 Inflammasome

Advanced Science, EarlyView.
The illustration of THBS1+ macrophages exacerbate MCs via SDC4‐dependent activation of the NLRP3 inflammasome. THBS1+ macrophage subpopulation was identified in MCs through single‐cell RNA sequencing. C. acnes and its metabolites activate THBS1 expression in macrophages via the TLR signaling pathway.
Xiangxi Kong, Qize Xue, Xiaoan Wei, Jie Li, Bao Huang, Weishao Chen, Zimin Cai, Tao Yang, Chengjun Yao, Jiayan Jin, Bohan Cai, Xuyang Zhang, Junhui Liu, Haihao Wu, Jian Chen, Zhi Shan, Fengdong Zhao   +16 more
wiley   +1 more source

Musculoskeletal symptoms in SARS-CoV-2 (COVID-19) patients

Journal of Orthopaedic Surgery and Research, 2020
Lucio Cipollaro, Lorenzo Giordano, Johnny Padulo, Francesco Oliva, Nicola Maffulli   +4 more
doaj   +1 more source

Is there a subgroup of females with patellofemoral pain syndrome likely to benefit from proximal control exercises?

Physiotherapy Quarterly
Introduction Patellofemoral pain syndrome (PFPS) is one of the most popular complaints among young females. Proximal hip control exercises can improve hip strength and reduce the stresses and pain.
Khaled A. Shalash, Abd El Rahman Chabara, Ahmad Hamdi Azzam, Nabil A. Mohamed, Ahmed M. ElMelhat   +4 more
doaj   +1 more source

Large‐scale Whole‐Exome Sequencing Defines the Protein‐Coding Architecture of Retinal Structure, Visual Function, and Major Blinding Diseases

Advanced Science, EarlyView.
Large‐scale whole‐exome sequencing in 356,982 UK Biobank participants defines the protein‐coding architecture of retinal structure, visual function, and major blinding diseases. Pleiotropic genes, including CFI, C3, and RIOX1, bridge multiple retinal phenotypes, while experimental validation of FYB2 implicates RPE barrier dysfunction, providing ...
Jianqing Li, Yijun Ge, Jingxiao Du, Liu Yang, Bangsheng Wu, Chenyue Hang, Mengxi Shen, Yimin Mao, Ting Zhang, Qiyu Bo, Tianyuan Zhao, Yutian Jiao, Yazhi Wang, Shunxiang Gao, Jieqiong Chen, Junran Sun, Tong Li, Huixun Jia, Yang Dou, Wei Cheng, Xiaoling Wan, Jintai Yu, Xiaodong Sun, Bai Lu   +23 more
wiley   +1 more source

Prospective associations between 24-h device-measured occupational and leisure-time physical activity and register-based musculoskeletal-related primary healthcare utilization among Danish workers

Scientific Reports
Musculoskeletal pain is a leading cause of seeking care and imposes an immense economic burden to the healthcare systems. The guidelines recommend physical activity for managing musculoskeletal pain but do not differentiate between occupational and ...
Stavros Kyriakidis, Søren Mose, Andreas Holtermann, Charlotte Diana Nørregaard Rasmussen, Nidhi Gupta, Karen Søgaard   +5 more
doaj   +1 more source