Results 171 to 180 of about 18,542,654 (255)

Mitochondrial Quality Control in Degenerative Musculoskeletal Diseases: Signaling Networks and Therapeutic Landscapes

Advanced Science, EarlyView.
Mitochondrial quality control (MQC) collapse redefines osteoarthritis, intervertebral disc degeneration, and osteoporosis as disorders of organelle dysfunction. Damaged mitochondria leak mtDNA and metabolites, driving cGAS‐STING inflammation, epigenetic reprogramming, and metabolic memory.
Haiyang Gao, Zhangrong Cheng, Xianglong Chen, Wenbo Wu, Wang Wu, Zimu Yu, Cao Yang, Yukun Zhang   +7 more
wiley   +1 more source

Concerns on modeling postmenopausal osteoporosis on young female rats

Journal of Orthopaedic Surgery and Research, 2019
Pavlos Lelovas, Ismene Dontas
doaj   +1 more source

Granular Cell Tumors of the Musculoskeletal System and Peripheral Nerves: A Systematic Review of Clinical Presentations, Treatments, and Outcomes. [PDF]

Diagnostics (Basel)
Ipponi E, D'Arienzo A, Campo FR, Gentili F, Cosseddu F, Andreani L, Parchi PD.   +6 more
europepmc   +1 more source

Symptom‐Driven Prediction of Chronic Multimorbidity with a Macro–Micro Heterogeneous Graph Neural Network

Advanced Science, EarlyView.
Clinical symptoms offer a window into multimorbidity. A macro‐micro heterogeneous graph neural network integrates clinical records with biomedical knowledge to improve patient‐level symptom‐disease association learning and visit‐level multimorbidity completion.
Yiheng Ye, Miaoru Han, Siqiao Tang, Zongxiang Zhang, Haichen Shen, Bingzhen Sun, Yan Zhang, Xiaodong Chu, Lijuan Deng, Chaoyang Zheng, Qingchun Huang, Kun Bao, Ronghua Zhang, Yong Wang, Fengwei Zhang, Xiaoli Chu   +15 more
wiley   +1 more source

The role of the lymphatic system in musculoskeletal system health and disease: research progress and future directions. [PDF]

Bone Res
Luo Y, Song J, Zheng S, Sun J, Liu G, Xiao Z, Opoku M, Arthur Vithran DT, Zhou J, Xiao W, Li Y.   +10 more
europepmc   +1 more source

Mechanical Distraction Engages a Neuro‐Immune Program to Drive Regenerative Soft‐Tissue Healing in Ilizarov Bone Transport

Advanced Science, EarlyView.
Ilizarov bone transport accelerates healing of soft‐tissue wounds through unclear mechanisms. In a rat model, sustained mechanical distraction elicits calcitonin gene‐related peptide (CGRP)‐dominant sensory reinnervation, creating a niche that shifts immune cells from inflammatory to repair‐promoting states and speeds re‐epithelialization.
Yueliang Zhu, Jiayu Chen, Xuehuan Wen, Kaijia Tang, Ling Gao, Chenxing Wang, Yixuan Feng, Si‐He Qin, Tao Chen, Xiaohua Yu   +9 more
wiley   +1 more source

Development, validation, and biomechanical evaluation of a high-fidelity finite element model of the forearm musculoskeletal system​. [PDF]

BMC Musculoskelet Disord
Shang RG, Xie SY, Liao LQ, Qin GZ, Zhu XY, Wang ZH, Xie JH, Li YK, Yang H, Gu RB.   +9 more
europepmc   +1 more source

Improving Post‐Fall Assessment Documentation in Older Inpatients Using a Structured Falls Proforma: A Retrospective Cohort Study

AGING MEDICINE, EarlyView.
Falls among hospital inpatients are associated with significant morbidity and require comprehensive post‐fall assessment. This retrospective cohort study evaluated documentation completeness following inpatient falls in older adults and compared assessments completed using a structured Falls Proforma with standard documentation methods.
Ella V. Brockwell‐Mole, Dujinthan Jayabalan, Su Kitchen, Minoti Bhagat   +3 more
wiley   +1 more source

Effects of Artificial Sweeteners on the Musculoskeletal System: A Systematic Review of Current Evidence. [PDF]

Nutrients
Xu X, Wang Q, Li B, Liu C, Cui C, Yi M, Zhai L, Wong RMY, Zhang N, Cheung WH.   +9 more
europepmc   +1 more source

Patterns of Radiologic Service Utilization and Imaging Expenditure in Supercentenarians in Colombia

AGING MEDICINE, EarlyView.
Analysis of Colombian administrative health data from 2014 to 2023 identified a distinct pattern of radiologic service utilization among supercentenarians (≥ 110 years). General radiology, ultrasound, and computed tomography were the most frequently used modalities, accounting for most imaging examinations.
Gabriela Puentes, Oscar Espinosa, Valeria Bejarano, Angela Guarnizo   +3 more
wiley   +1 more source