Results 81 to 90 of about 54,260 (235)
Novel approaches for drug development against chronic primary pain: A systematic review
British Journal of Pharmacology, EarlyView.Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Allergic contact dermatitis (ACD) is a frequent inflammatory skin disease with limited therapeutic options. While neuronal Transient Receptor Potential Ankyrin 1 (TRPA1) has been implicated in ACD, the role of keratinocyte TRPA1 remains unclear.
Areej Jaber +8 more
wiley +1 more source
The ALS‐associated E425K mutation uncouples DNAJC7 from the Hsp70 chaperone cycle
The FEBS Journal, EarlyView.DNAJC7 is a J‐domain protein that plays a key role in protein quality control by regulating Hsp70 activity and preventing protein aggregation. We find that the ALS‐associated E425K mutation in DNAJC7 disrupts productive interaction and activation of Hsp70, thereby blocking the transfer and refolding of client proteins such as TDP‐43.
Bar Elmaleh +2 more
wiley +1 more source
Journal of Applied Entomology, EarlyView.ABSTRACT Biological control in high tunnel systems can be optimised by matching predator species to seasonal environmental conditions. We evaluated the predatory efficacy of syrphid flies (Toxomerus marginatus (Say), Eupeodes americanus (Fabricius)) and lacewings (Chrysoperla carnea (Stephens), Chrysoperla rufilabris (Burmeister)) across laboratory ...
Allison Zablah +3 more
wiley +1 more source
Journal of Agrarian Change, EarlyView.ABSTRACT The agroecological practices of ethnic minority farmers in Vietnam's northern uplands are being reshaped by intersecting pressures of land‐use reform, market integration, and state‐backed crop promotion. Among Hmong communities in the south of Lào Cai Province (former Yên Bái Province) cinnamon was once valued primarily for its medicinal ...
Mélie Monnerat, Sarah Turner
wiley +1 more source
Can LED Lighting Be a Sustainable Solution for Producing Nutritionally Valuable Microgreens?
HorticulturaeWith its quality, intensity, and photoperiod, light is a decisive abiotic factor that directly influences plant biomass and the accumulation of specialized metabolites (SMs).
Roberta Vrkić +3 more
doaj +1 more source
A survey on the presence of undesirable botanical substances in feed in the European Union [PDF]
Biotechnologie, Agronomie, Société et Environnement, 2009 Directive 2002/32/EC of the European Parliament and of the Council of 7 May 2002 on undesirable substances in animal feed lists a range of substances from botanical origin (weed seeds) and additionally some chemical compounds directly originating from ...
van Raamsdonk LWD. +2 more
doaj
Strategies for Legitimizing Regeneration in Supply Chain Fields
Journal of Supply Chain Management, EarlyView.ABSTRACT In view of escalating environmental degradation, regenerative business has been proposed to restore social–ecological systems. However, as regeneration fundamentally departs from mainstream approaches and lacks commonly accepted standards, it suffers from a liability of newness that hampers its broader legitimation and adoption.
Veronica Devenin +3 more
wiley +1 more source
Zoonotic anxieties: The cultural politics of Nepal's quest for pandemic preparedness
Medical Anthropology Quarterly, EarlyView.Abstract Based on fieldwork conducted in Nepal (2022–2024) and by paying attention to how local and transnational notions of epidemiological risk are deployed, this ethnography introduces the concept of “zoonotic anxieties” to make sense of the multi‐species relational ethos that contemporary global health regimes propose.
Max D. López Toledano +3 more
wiley +1 more source