Results 21 to 30 of about 73,569 (303)

Occurrence of the potent mutagens 2- nitrobenzanthrone and 3-nitrobenzanthrone in fine airborne particles

open access: yesScientific Reports, 2019
Polycyclic aromatic compounds (PACs) are known due to their mutagenic activity. Among them, 2-nitrobenzanthrone (2-NBA) and 3-nitrobenzanthrone (3-NBA) are considered as two of the most potent mutagens found in atmospheric particles. In the present study
A. G. Santos   +2 more
semanticscholar   +1 more source

Proteome Profiling of the Mutagen-Induced Morphological and Yield Macro-Mutant Lines of Nigella sativa L.

open access: yesPlants, 2019
In the present investigation, the leaf proteome profile of the macro-mutant lines of Nigella sativa L. was analyzed to identify the key proteins involved in the expression of traits associated with the morphology, seed yield, and content of thymoquinone.
Ambreen Asif   +5 more
doaj   +1 more source

Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1975
About 300 carcinogens and non-carcinogens of a wide variety of chemical types have been tested for mutagenicity in the simple Salmonella/microsome test.
J. McCann, E. Choi, E. Yamasaki, B. Ames
semanticscholar   +1 more source

Induced chlorophyll mutations in Gloriosa superba

open access: yesElectronic Journal of Plant Breeding, 2021
The present experiment was carried out to study the spectrum of chlorophyll mutations, mutagenic effectiveness and efficiency in Gloriosa superba seeds using both chemical and physical mutagens.
S. Padmapriya* and K. Rajamani
doaj   +1 more source

The Mutagenic Impact of Environmental Exposures in Human Cells and Cancer: Imprints Through Time

open access: yesFrontiers in Genetics, 2021
During life, the DNA of our cells is continuously exposed to external damaging processes. Despite the activity of various repair mechanisms, DNA damage eventually results in the accumulation of mutations in the genomes of our cells.
Axel Rosendahl Huber   +5 more
doaj   +1 more source

Carcinogens are mutagens: a simple test system combining liver homogenates for activation and bacteria for detection.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1973
18 Carcinogens, including aflatoxin B(1), benzo(a)pyrene, acetylaminofluorene, benzidine, and dimethylamino-trans-stilbene, are shown to be activated by liver homogenates to form potent frameshift mutagens.
B. Ames, W. Durston, E. Yamasaki, F. Lee
semanticscholar   +1 more source

Genome-wide somatic mutation analysis via Hawk-Seq™ reveals mutation profiles associated with chemical mutagens

open access: yesArchives of Toxicology, 2019
It is difficult to identify mutagen-induced genome-wide somatic mutations using next generation sequencing; hence, mutagenic features of each mutagen and their roles in cancer development require further elucidation.
S. Matsumura   +5 more
semanticscholar   +1 more source

A mathematical model for cancer risk and accumulation of mutations caused by replication errors and external factors.

open access: yesPLoS ONE, 2023
Replication errors influence mutations, and thus, lifetime cancer risk can be explained by the number of stem-cell divisions. Additionally, mutagens also affect cancer risk, for instance, high-dose radiation exposure increases lifetime cancer risk ...
Kouki Uchinomiya, Masanori Tomita
doaj   +1 more source

Assessment of genotoxic and mutagenic effects of food products by bioassay methods

open access: yesТеория и практика переработки мяса, 2021
The current state of studies on application and safety of food additives in various technologies for food production is examined. Considerable attention should be given to studies dedicated to analysis of food safety criteria due to a possibility of ...
M. V. Zaytseva
doaj   +1 more source

Induced Mutations Unleash the Potentials of Plant Genetic Resources for Food and Agriculture

open access: yesAgronomy, 2013
The options for increasing food production by at least 70% over the next four decades so as to keep pace with a rapidly increasing human population are bedeviled by erratic climatic conditions, depleted arable lands, dwindling water resources and by the ...
Chikelu Mba
doaj   +1 more source

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