Results 21 to 30 of about 53,897 (283)

Carcinogens are mutagens: a simple test system combining liver homogenates for activation and bacteria for detection.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1973
18 Carcinogens, including aflatoxin B(1), benzo(a)pyrene, acetylaminofluorene, benzidine, and dimethylamino-trans-stilbene, are shown to be activated by liver homogenates to form potent frameshift mutagens.
B. Ames, W. Durston, E. Yamasaki, F. Lee
semanticscholar   +1 more source

Genome-wide somatic mutation analysis via Hawk-Seq™ reveals mutation profiles associated with chemical mutagens

open access: yesArchives of Toxicology, 2019
It is difficult to identify mutagen-induced genome-wide somatic mutations using next generation sequencing; hence, mutagenic features of each mutagen and their roles in cancer development require further elucidation.
S. Matsumura   +5 more
semanticscholar   +1 more source

A mathematical model for cancer risk and accumulation of mutations caused by replication errors and external factors.

open access: yesPLoS ONE, 2023
Replication errors influence mutations, and thus, lifetime cancer risk can be explained by the number of stem-cell divisions. Additionally, mutagens also affect cancer risk, for instance, high-dose radiation exposure increases lifetime cancer risk ...
Kouki Uchinomiya, Masanori Tomita
doaj   +1 more source

A systematic review on physical mutagens in rice breeding in Southeast Asia [PDF]

open access: yesPeerJ, 2023
In the 1920s, Lewis Stadler initiated the introduction of permanent improvements to the genetic makeup of irradiated plants. Since then, studies related to breeding mutations have grown, as efforts have been made to expand and improve crop productivity ...
Rosina Baadu   +4 more
doaj   +2 more sources

Human urinary mutagenicity after wood smoke exposure during traditional temazcal use. [PDF]

open access: yes, 2014
In Central America, the traditional temazcales or wood-fired steam baths, commonly used by many Native American populations, are often heated by wood fires with little ventilation, and this use results in high wood smoke exposure.
HOLLAND, Nina   +8 more
core   +3 more sources

Assessment of genotoxic and mutagenic effects of food products by bioassay methods

open access: yesТеория и практика переработки мяса, 2021
The current state of studies on application and safety of food additives in various technologies for food production is examined. Considerable attention should be given to studies dedicated to analysis of food safety criteria due to a possibility of ...
M. V. Zaytseva
doaj   +1 more source

The paradigm of induced chemical mutagenesis of Allium sativum L. [PDF]

open access: yesE3S Web of Conferences, 2020
The scheme of induced chemical mutagenesis of treatment of Allium sativum L. air bulbs of winter garlic bred by FSBSI “Research Institute of Agriculture of Crimea”, grown in a breeding nursery, has been developed. Two chemical mutagens of the first group,
Nemtinov V I   +6 more
doaj   +1 more source

DNA Repair in Drosophila: Mutagens, Models, and Missing Genes

open access: yesGenetics, 2017
The numerous processes that damage DNA are counterbalanced by a complex network of repair pathways that, collectively, can mend diverse types of damage. Insights into these pathways have come from studies in many different organisms, including Drosophila
J. Sekelsky
semanticscholar   +1 more source

Genotoxicity assessment of piperitenone oxide: an in vitro and in silico evaluation [PDF]

open access: yes, 2017
Piperitenone oxide, a natural flavouring agent also known as rotundifolone, has been studied for the genotoxicity assessment by an integrated in vitro and in silico experimental approach, including the bacterial reverse mutation assay, the micronucleus ...
Abete, Lorena   +9 more
core   +1 more source

Induced Mutations Unleash the Potentials of Plant Genetic Resources for Food and Agriculture

open access: yesAgronomy, 2013
The options for increasing food production by at least 70% over the next four decades so as to keep pace with a rapidly increasing human population are bedeviled by erratic climatic conditions, depleted arable lands, dwindling water resources and by the ...
Chikelu Mba
doaj   +1 more source

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