Results 121 to 130 of about 1,179,318 (342)

The Consequences of Mutation during the Growth of Biochemical Mutants of Escherichia coli [PDF]

, 1948
Francis J. Ryan, Lillian K. Schneider
openalex   +1 more source

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology

Molecular Oncology, EarlyView.
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang, Anna Schritz, Nikolai Goncharenko, Guy Berchem   +3 more
wiley   +1 more source

Effect size of delayed freezing, diurnal variation, and hindgut location on the mouse fecal microbiome

iScience
Summary: Practical considerations in fecal sample collection for microbiome research include time to sample storage, time of collection, and hindgut position during terminal collections.
Kevin L. Gustafson, Zachary L. McAdams, Amber L. Russell, Rebecca A. Dorfmeyer, Giedre M. Turner, Aaron C. Ericsson   +5 more
doaj  

DIHYDROURACIL AS A GROWTH FACTOR FOR MUTANT STRAINS OFESCHERICHIA COLI [PDF]

, 1957
Irving J. Slotnick, Herbert Weinfeld
openalex   +1 more source

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

Molecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou, Aliki Ntzifa, Victoria Tserpeli, Ioanna Balgkouranidou, Alkistis Papatheodoridi, Evangelia Razis, Helena Linardou, Christos Papadimitriou, Amanda Psyrri, Flora Zagouri, Stylianos Kakolyris, Evi Lianidou   +11 more
wiley   +1 more source

Characterization of desnutrin functional domains: critical residues for triacylglycerol hydrolysis in cultured cells[S]

Journal of Lipid Research, 2010
Murine desnutrin/human ATGL is a triacylglycerol (TAG) hydrolase with a predicted catalytic dyad within an α-β hydrolase fold in the N-terminal region.
Robin E. Duncan, Yuhui Wang, Maryam Ahmadian, Jennifer Lu, Eszter Sarkadi-Nagy, Hei Sook Sul   +5 more
doaj  

Utilization of alpha-Ketoadipic Acid by Lysineless Ophiostoma Mutants. [PDF]

, 1950
Sune Bergsröm, Max Rottenberg, S. Laurell, Max Rottenberg   +3 more
openalex   +1 more source

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

Molecular Oncology, EarlyView.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa, Zdenka Herudkova, Jan Hyl, Jakub Vlazny, Filip Sokol, Kvetoslava Matulova, Adam Folta, Jakub Hynst, Lucy Vojtova, Leos Kren, Martin Repko, Zdenek Racil, Jiri Mayer, Martin Culen   +13 more
wiley   +1 more source

Phenotypic mixing and hiding may contribute to memory in viral quasispecies [PDF]

BMC Microbiology 3:11 (2003), 2003
Background. In a number of recent experiments with food-and-mouth disease virus, a deleterious mutant, was found to avoid extinction and remain in the population for long periods of time. This observation was called quasispecies memory. The origin of quasispecies memory is not fully understood. Results.
arxiv  

THE REPLACEMENT OF PARA-AMINOBENZOIC ACID BY METHIONINE IN THE GROWTH OF A NEUROSPORA MUTANT [PDF]

, 1950
Bernard L. Strehler
openalex   +1 more source