Results 241 to 250 of about 2,159,893 (336)

Histone modification cross-talk and protein complex diversification confer plasticity to Polycomb repression. [PDF]

Genes Dev
Bonnet J, Triantopoulou E, Birnhäupl J, Lu C, Fuller MT, Müller J.   +5 more
europepmc   +1 more source

Micturition defects and altered bladder function in the klotho mutant mouse model of aging.

, 2020
Sarah N. Bartolone, Elijah Ward, Zunyi Wang, Bernadette Zwaans, Michael B. Chancellor, Dale E. Bjorling, Laura E. Lamb   +6 more
openalex   +1 more source

Collection and analysis of Arabidopsis color mutants [PDF]

, 2004
Hiromitsu Nakanishi, Kenji Suzuki, Takashi Jouke, Ritsuko Kodaira, Goro Taguchi, Mitsuo Okazaki   +5 more
openalex  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Fine mapping and transcriptomics reveal OSG function in regulation of grain size and pollen fertility in rice (Oryza sativa). [PDF]

PLoS One
Zhao S, Zhang S, Xu W, Fang S, Liu M, Wang L, Zhang X, Chen B, Wei S, Zhao H.   +9 more
europepmc   +1 more source

1I1045 Recent developments in ProTherm : Thermodynamic Database for Proteins and Mutants

, 2002
Abdulla Bava Kuttunganakam, M. Michael Gromiha, Hatsuho Uedaira, K. Kitajima, Akinori Sarai   +4 more
openalex   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Identification of a Leaf Cuticular Wax Biosynthesis Gene <i>BrCER2</i> in Chinese Cabbage (<i>Brassica rapa</i> L. ssp. <i>pekinensis</i>). [PDF]

Plants (Basel)
Huang Y, Bai X, Ying W, Wang Y, Yang C, Huang M, Xu L, Fang H, Wu J, Zang Y.   +9 more
europepmc   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

A genome-wide genetic screen reveals the P2Y2-integrin axis as a stabilizer of EGFR mutants in non-small cell lung cancer (NSCLC). [PDF]

Sci Adv
Du Y, Wang W, Goh HC, Vaiyapuri TS, Raju A, Hsiao YC, Wang CC, Agrawal V, Mohideen NF, Mohd Mazian NB, Karatekin F, Wang WK, Lakshmanan M, Gupta K, Chang H, Le Guezennec X, Bard F, Tan DSW, Tergaonkar V, Hung MC, Liu X, Hong W, Boopathy GTK.   +22 more
europepmc   +1 more source