Results 241 to 250 of about 2,088,899 (353)

A sterile and extremely dwarf mutant occurred in a theoretically pure line of rice

, 1942
盛永 俊太郎, 栗山 英雄, 青木 政春   +2 more
openalex   +2 more sources

ENVIRONMENTAL FACTORS OTHER THAN TEMPERATURE AFFECTING FACET NUMBER IN THE BAR-EYED MUTANT OF DROSOPHILA [PDF]

, 1920
Joseph Krafka
openalex   +1 more source

Structural and functional impact of the p.R163C mutation in the conserved palindromic motif within the C-terminal domain of human αB-crystallin. [PDF]

PLoS One
Baharvand A, Mariam Z, Shahsavani MB, Somee LR, Zarei I, Amanlou M, Deganutti G, Saboury AA, Moosavi-Movahedi AA, Yousefi R.   +9 more
europepmc   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

NATURAL MUTATIONS IN INBRED LINES OF MAIZE AND THEIR HETEROTIC EFFECT. II. COMPARISON OF MOTHER LINE VS. MUTANT WHEN OUTCROSSED TO UNRELATED INBREDS [PDF]

, 1956
Josef F Schuler, G. F. Sprague
openalex   +1 more source

A single-nucleotide mutation of G301A in <i>GaIAA14</i> confers leaf curling in <i>Gossypium arboreum</i>. [PDF]

Front Plant Sci
Miao P, Zhang H, Xu Y, Zhang R, Hao Y, Song G, Liu J.   +6 more
europepmc   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

RECOMBINATIONS OF MUTANT PHAGES OF BACILLUS MEGATHERIUM 899A [PDF]

, 1953
James S. Murphy
openalex   +1 more source

Beta-Catenin Mutations Can Impact on the Interplay Between Tumor and Immune Cells and Hepatic Microbiota in Hepatocellular Cancer. [PDF]

J Hepatocell Carcinoma
Ota Y, Driscoll J, Hill AR, Yan IK, Patel T.   +4 more
europepmc   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source