Results 241 to 250 of about 2,828,087 (336)

Integrated genomic and structural dissection of melanism in Indian leopard (Panthera pardus fusca). [PDF]

BMC Genomics
Ghosh A, Kumar S, Porob P, Thakur M, Shukla M, Kumar S, Nidhi S, Singh A.   +7 more
europepmc   +1 more source

LBA3 SOLTI-1507 IPATHER: Primary results of the phase Ib study of ipatasertib (IPAT) and dual anti-HER2 therapy with trastuzumab and pertuzumab (HP) in patients (pts) with PIK3CA mutant (mut) HER2+ advanced breast cancer (ABC)

Maila Dayane Capuchinho de Oliveira, Eva Ciruelos, Serafín Morales, F.J. Salvador Bofill, Vanesa Garcı́a, J. Gavilá-Gregori, Alicia Mosquera, Estela Vega Alonso, Fernando Henao, S. Servitja Tormo, Pablo Tolosa, G. Villacampa Javierre, Fernando Salvador, M. Paes Dias, J.M. Ferrero-Cafiero, Xavier González, T. Pascual, C. Saura Manich   +17 more
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

The chordoid glioma <i>PRKCA</i> D463H mutation is a kinase inactive, gain-of-function allele that induces early-onset chondrosarcoma in mice. [PDF]

Sci Signal
Calleja V, Henry JC, Cobbaut M, Sewell J, Rizzoti K, Houghton F, Boeing S, Anyanwu N, Varsani-Brown S, Snoeks T, Suárez-Bonnet A, Priestnall SL, McDonald NQ, Cameron AJM, Parker PJ.   +14 more
europepmc   +1 more source

Functional expression of native and mutant Y←1 receptors in stably transfected adenocarcinoma cell lines.

, 1998
Nicholas D. Holliday
openalex   +1 more source

Figure S3 from Combination of the MTA-Cooperative PRMT5 Inhibitor BMS-986504 and KRAS Inhibitors Is an Effective Treatment Strategy for <i>MTAP</i>-Deleted <i>KRAS</i>-Mutant Pancreatic Cancer

Kristina Drizyte‐Miller, Lars D. Engstrom, Jeffrey A. Klomp, Clint A. Stalnecker, Addison G. Stamey, Khalilah E. Taylor, Mallory K. Roach, Ryan Robb, Laura Waters, Andrew Calinisan, Seamus Degan, Wen-Hsuan Chang, Xousaen M. Helu, David Nguyen, Elisa Baldelli, Mariaelena Pierobon, Emanuel F. Petricoin, David M. Briere, Jill Hallin, James G. Christensen, Kirsten L. Bryant, Adrienne D. Cox, Peter Olson, Channing J. Der   +23 more
openalex   +1 more source

Cardiac contractility, motor function, and cross‐bridge kinetics in N47K‐RLC mutant mice [PDF]

, 2017
Li Wang, Katarzyna Kaźmierczak, Chen‐Ching Yuan, Sunil Kumar Yadav, Masataka Kawai, Danuta Szczesna‐Cordary   +5 more
openalex   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Computational evaluation of AKT2 mutations reveals R274H and R467W as potential drivers of protein instability and inhibitor resistance in cancer therapy. [PDF]

PLoS One
Runa SA, Tonmoy MIQ, Islam MA, Islam MA.
europepmc   +1 more source

Bromatologia de mutantes de Urochloa brizantha cv. Marandú com diferentes hábitos de crescimento

, 2018
Camila Baptistão Zaniboni
openalex   +1 more source