Results 251 to 260 of about 2,913,254 (384)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Iron overload disrupts lipid desaturation through SKN-1 signaling in <i>C. elegans</i>: implications for ferroptosis-based immunomodulatory biomaterials. [PDF]

Mater Today Bio
Dong Z, Liao Y, Shi H, Zhang J, Lin J, Liu Q, Zhang S, Fan X, Liu B, Wang Y, Zheng Y, Gao L.   +11 more
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Molecular analysis of lacI mutants from transgenic fibroblasts exposed to 1,2-epoxybutene [PDF]

, 1998
Christopher J. Saranko
openalex   +1 more source

A multifocal IDH-mutant glioma with differential response to IDH inhibition: Role of quantitative neuroimaging. [PDF]

Radiol Case Rep
Ibrahim O, Cho NS, Le VL, Sanvito F, Yao J, Teraishi A, Lai A, Nghiemphu PL, Salamon N, Rodriguez FJ, Everson R, Cloughesy TF, Ellingson BM.   +12 more
europepmc   +1 more source

Mutant Ninja viruses [PDF]

Hepatology, 2015
openaire   +2 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Targeting mutant NRAS signaling pathways in melanoma

, 2016
Ha Linh Vu, Andrew E. Aplin
openalex   +2 more sources

New tool for studying interactions of components of ribonucleic acid polymerase: rifampin-dependent mutants [PDF]

, 1979
Eric R. Dabbs
openalex   +1 more source

Exploiting evolutionary diversity of cellulose synthase catalytic subunits to generate novel cellulose microfibril structure in Arabidopsis. [PDF]

J Exp Bot
Kumar M, Gomez LD, Faas L, Turner S.
europepmc   +1 more source