Results 21 to 30 of about 1,483,986 (159)

Oryza Tag Line, a phenotypic mutant database for the Genoplante rice insertion line library [PDF]

, 2008
To organize data resulting from the phenotypic characterization of a library of 30 000 T-DNA enhancer trap (ET) insertion lines of rice (Oryza sativa L cv.
Bouniol, M., Gay, Céline, Perez, Pascual, Biderre-Petit, C., Courtois, Brigitte, Gay, C, Johnson, Alexander a T, Benoit Morel, J., Courtois, B., Barnola, Isabelle, Sallaud, C, Morel, Jean Benoît, Sallaud, C., Bouniol, Matthieu, Larmande, Pierre, Larmande, P., Ghesquière, Alain, Barnola, I, Ruiz, M., Lorieux, M., Martin, J., Gay, C., Perez, P., Sallaud, Christophe, Guiderdoni, Emmanuel, Martin, Jérôme, Johnson, Alexander A.T., Bourgis, Fabienne, Lorieux, Mathias, Barnola, I., Perin, C., Bourgis, F., Morel, Jean-Benoit, Johnson, A., Périn, Christophe, Biderre-Petit, Corinne, Bouniol, M, Ruiz, Manuel, Ruíz, M.E., Droc, G., Droc, Gaëtan, Guiderdoni, E., Ghesquiere, A.   +42 more
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Egy virulencia regulátor mutáns Salmonella enterica törzs mint kereszt-immunitást biztosító orális vakcina jelölt vizsgálata = Investigation of a virulence regulator mutant strain of Salmonella enterica as a candidate for live oral vaccine providing cross-immunity [PDF]

, 2008
Kutatásaink során egy Salmonella rfaH mutánst mint potenciális vakcina jelöltet vizsgáltunk több aspektusból. Mivel az RfaH fehérje egy transzkripciós regulátor, vizsgáltuk, hogy mely virulencia faktorokra kifejtett hatása okozza a vakcina törzs ...
Nagy, Gábor
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Inactivation and inducible oncogenic mutation of p53 in gene targeted pigs. [PDF]

, 2012
Mutation of the tumor suppressor p53 plays a major role in human carcinogenesis. Here we describe gene-targeted porcine mesenchymal stem cells (MSCs) and live pigs carrying a latent TP53(R167H) mutant allele, orthologous to oncogenic human mutant TP53 ...
Eckhard Wolf, Marlene Edlinger, Marlene Edlinger (133272), Eckhard Wolf (39870), Krzysztof Flisikowski (133283), Mayuko Kurome, Claudia Merkl (133270), Kurome, Mayuko, Claudia Merkl, Alexander Kind, Valeri Zakhartchenko, Flisikowski, Krzysztof, Simon Leuchs (133268), Nousin Rezaei, Anja Saalfrank, Valeri Zakhartchenko (133278), Marina Durkovic (133273), Marina Durkovic, Krzysztof Flisikowski, Flisikowska, Tatiana, Kessler, Barbara, Saalfrank, Anja, Merkl, Claudia, Schnieke, Angelika, Simon Leuchs, Kind, Alexander, Zakhartchenko, Valeri, Barbara Kessler (133280), Alexander Kind (133287), Edlinger, Marlene, Mayuko Kurome (133277), Wolf, Eckhard, Rezaei, Nousin, Nousin Rezaei (133275), Angelika Schnieke (133290), Tatiana Flisikowska, Angelika Schnieke, Anja Saalfrank (133269), Tatiana Flisikowska (133271), Barbara Kessler, Leuchs, Simon, Durkovic, Marina   +41 more
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Structural Basis for Inhibition of Mutant EGFR with Lazertinib (YH25448) [PDF]

, 2022
Lazertinib (YH25448) is a novel third-generation tyrosine kinase inhibitor (TKI) developed as a treatment for EGFR mutant non-small cell lung cancer. To better understand lazertinib inhibition at the molecular level, we determined crystal structures of ...
Pamela, Hershberger, Tyler, Beyett, Bo, Yang, David, Heppner, Calvin, Pham, Ilse, Schaeffner, Stefan, Laufer, Blessing, Ogboo, Tatiana, Shaurova, Florian, Wittlinger, Michael, Eck   +10 more
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Neuroinflammation by cytotoxic T-lymphocytes impairs retrograde axonal transport in an oligodendrocyte mutant mouse [PDF]

, 2012
Mice overexpressing proteolipid protein (PLP) develop a leukodystrophy-like disease involving cytotoxic, CD8+ T-lymphocytes. Here we show that these cytotoxic T-lymphocytes perturb retrograde axonal transport.
Groh Janos, Dennis Klein, Spahn, Irene, Klein Dennis, Huber, M., Spahn, I., Ip, Chi Wang, Nave, Klaus-Armin, Diem Ricarda, Groh, J., Ip Chi Wang, Huber, Marianne, Sarah K. Williams, Rudolf Martini, Martini Rudolf, Kroner, A., Janos Groh, Ip, C., Williams, S., Edgar, Julia M., Kroner Antje, Huber Marianne, Ip, C.W., Martini, Rudolf, Nave Klaus-Armin, Martini, R., Antje Kroner, Chi Wang Ip, Diem, Ricarda, Edgar Julia M., Kroner, Antje, Julia M Edgar, Williams, Sarah K., Nave, K., Marianne Huber, Julia M. Edgar, Spahn Irene, Diem, R., Klaus-Armin Nave, Ricarda Diem, Sarah K Williams, Groh, Janos, Klein, Dennis, Klein, D., Edgar, J., Edgar, J.M., Williams Sarah K., Irene Spahn   +47 more
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Defining the requirements for the pathogenic interaction between mutant calreticulin and MPL in MPN [PDF]

, 2018
Mutations in calreticulin (CALR) are phenotypic drivers in the pathogenesis of myeloproliferative neoplasms. Mechanistic studies have demonstrated that mutant CALR binds to the thrombopoietin receptor MPL, and that the positive electrostatic charge of ...
Gabriel Birrane, Nouran S. Abdelfattah, Edwin Chen, Mullally, A., Rivera, JF, Natalie Florescu, Danielle Beeson, Chen, E, Chen, E., Ko, A, Elf, S, Abdelfattah, N.S., Jeanne F. Rivera, Florescu, N, Mullally, A, Elf, S., Florescu, N., Ann Mullally, Birrane, G., Ko, A., Shannon Elf, April J. Baral, Birrane, G, Baral, A.J., Beeson, D., Baral, AJ, Amy Ko, Abdelfattah, NS, Beeson, D, Rivera, J.F.   +29 more
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The cellular fate of mutant rhodopsin: quality control, degradation and aggresome formation [PDF]

, 2002
Mutations in the photopigment rhodopsin are the major cause of autosomal dominant retinitis pigmentosa. The majority of mutations in rhodopsin lead to misfolding of the protein.
Munro, PMG, Cheetham, ME, Saliba, RS, Luthert, PJ   +3 more
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Genetic and phenotypic characterisation of an Arabidopsis thaliana jasmonic acid signalling mutant, jam2 [PDF]

, 2003
Bibliography: leaves 72-77.Jasmonic acid (JA) is a plant hormone with diverse functions, ranging from development to stress responses. Moreover, a role for JA in mediating defence against pathogen attack has been established, seemingly specific against ...
Sanderson, Micheline
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A Brazilian glycoprotein E-negative bovine herpesvirus type 1.2a (BHV-1.2a) mutant is attenuated for cattle and induces protection against wild-type virus challenge [PDF]

, 2002
The authors previously reported the construction of a glycoprotein E-deleted (gE-) mutant of bovine herpesvirus type 1.2a (BHV-1.2a). This mutant, 265gE-, was designed as a vaccinal strain for differential vaccines, allowing the distinction between ...
Esteves, P.A., Lima, M., de, Rijsewijk, F.A.M., Franco, A.C., Flores, E.F., Weiblen, R., Roehe, P.M., Spilki, F.R.   +7 more
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Deficiency in mRNA splicing in a cytochrome c mutant of neurospora crassa [PDF]

, 1987
Molecular cloning and characterization of cytochrome c cDNA clones of Neurospora crassa wild-type (74A) and a cytochrome c-deficient mutant (cyc1-1) are described.
Tropschug, Maximilian, Stuart, Rosemary A., Neupert, Walter   +2 more
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