Results 31 to 40 of about 1,483,986 (159)

Disruption of the interaction of RAS with PI 3-kinase induces regression of EGFR-mutant-driven lung cancer

, 2020
RAS family GTPases contribute directly to the regulation of type I phosphoinositide 3-kinases (PI3Ks) via RAS-binding domains in the PI3K catalytic p110 subunits.
Bradley Spencer-Dene (1085), Gordon Stamp (55542), Julian Downward (49269), Sareena Rana (94145), Miguel M Murillo (8267778), Emma Nye (206817)   +5 more
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Biochemical and photosystem characteristics of wild-type and Chl b-deficient mutant in tree peony (Paeonia suffruticosa)

, 2021
In order to explore the adaptive strategies of tree peony yl1 mutant in response to photooxidative stress, the changes of biochemical parameters, chlorophyll fluorescence, and the modulated 820-nm reflection of yl1 mutant and wild-type plants were ...
S. LI, S. LI, S.D. CHEN, S.D. LIU, X.G. HOU, J.Z. WANG, J.Z. WANG, Q.S. CHANG, S.D. CHEN, L.X. ZHANG, L.X. ZHANG, Q.S. CHANG, Q.M. ZHANG, X.G. HOU, Q.M. ZHANG, S.D. LIU   +15 more
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Reduced gibberellin response affects ethylene biosynthesis and responsiveness in the Arabidopsis gai eto2-1 double mutant. [PDF]

, 2007
Ethylene and gibberellins (GAs) control similar developmental processes in plants. The role of ethylene is at least in part to regulate the accumulation of DELLA proteins, key regulators of plant growth, which suppress the GA response.
Decat, J, Baghour, M, Gerrit T. S. Beemster, Phillips, Andy L, Andy L. Phillips, Harberd, Nicholas P, Hedden, Peter, Jasper Dugardeyn, Dominique Van Der Straeten, Dugardeyn, Jasper, Hedden, P., Thomas Moritz, De Grauwe, L, Rieu, I, De Grauwe, Liesbeth, Beemster, G. T. S., Harberd, NP, Laury Chaerle, Decat, J., Beemster, GT, Van Der Straeten, D, Rieu, I., Harberd, Nicholas, Vriezen, Willem, Moritz, T., Jan Decat, Hedden, P, Wim H. Vriezen, Dugardeyn, J., Dugardeyn, J, Moritz, T, Phillips, AL, Moritz, Thomas, Beemster, Gerrit, Ivo Rieu, Decat, Jan, Vriezen, W. H., Van Der Straeten, Dominique, Nicholas P. Harberd, De Grauwe, L., Chaerle, L., Vriezen, WH, Peter Hedden, Rieu, Ivo, Harberd, N. P., Chaerle, L, Liesbeth De Grauwe, Beemster, GTS, Phillips, A. L., Chaerle, Laury, Van Der Straeten, D.   +50 more
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Degradation of vasopressin precursor and pathogenic mutants in diabetes insipidus [PDF]

, 2007
The nonapeptide hormone, arginine vasopressin, plays a decisive role in the regulation of fluid balance by reducing free water clearance through reabsorption of water in the renal collecting ducts.
Friberg, Michael
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Construction of a severely attenuated mutant of Mycobacterium tuberculosis for reducing risk to laboratory workers

, 2008
The ability to construct defined deletions of Mycobacterium tuberculosis has allowed many genes involved in virulence to be identified. Deletion of nutritional genes leads to varying levels of attenuation, presumably reflecting the need for a particular ...
Williams, A, Williams, Ann, Clark, S, Clark, Simon, Smith, D, Hatch, Graham, Movahedzadeh, F, Stoker, N G, Movahedzadeh, Farahnaz, Bacon, Joanna, Parish, T, LSHTM, Ten Bokum, A M C, Parish, Tanya, Hatch, G, Smith, Debbie, HPA, Bacon, J, ten Bokum, Annemieke, Stoker, Neil   +19 more
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Characterization and gene mapping of a chlorophyll-deficient mutant clm1 of Triticum monococcum L.

, 2013
Diploid wheat Triticum monococcum L. is a model plant for wheat functional genomics. Chlorophyll-deficient mutant (clm1) was identified during manual screening of the ethyl methanesulphonate (EMS)-treated M2 progenies of T.
R. Kumar, Y. Al-Attal, A. Nuru, S. Usmani, M. J. Ansari, K. Singh, A. Al-Ghamdi, H. S. Dhaliwal, A. A. Mohamed   +8 more
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Insight into the early steps of root hair formation revealed by the procuste1 cellulose synthase mutant of Arabidopsis thaliana [PDF]

, 2008
Background: formation of plant root hairs originating from epidermal cells involves selection of a polar initiation site and production of an initial hair bulge which requires local cell wall loosening. In Arabidopsis the polar initiation site is located
Singh, Sunil K., Singh, Manoj, Marchant, Alan, Fischer, Urs, Grebe, Markus, Singh, Sunil, Grebe, Markus,, Alan Marchant, Singh, Sunil,, Urs Fischer, Manoj Singh, Sunil K Singh, Markus Grebe   +12 more
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An ion beam–induced Arabidopsis mutant with marked chromosomal rearrangement

, 2017
Ion beams have been used as an effective tool in mutation breeding for the creation of crops with novel characteristics. Recent analyses have revealed that ion beams induce large chromosomal alterations, in addition to small mutations comprising base ...
Fujimoto, Satoru, 田中, 淳, 490660, Matsunaga, Sachihiro, 坂本, 綾子, 490662, 490661, 490659, 490658, 田中 淳, Thi, Thuong Lan Vo, 490664, 坂本 綾子, 490663   +13 more
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The Arabidopsis cer26 mutant, like the cer2 mutant, is specifically affected in the very long chain fatty acid elongation process [PDF]

, 2013
Plant aerial organs are covered by cuticular waxes, which form a hydrophobic crystal layer that mainly serves as a waterproof barrier. Cuticular wax is a complex mixture of very long chain lipids deriving from fatty acids, predominantly of chain lengths ...
Domergue, Frédéric, Pervent, Marjorie, Haslam, R. P., Pascal, S., Pascal, Stéphanie, Lessire, René, Vile, D., Joubès, Jérôme, Sorel, M., Lessire, R., Joubes, J., Bernard, A., Pervent, M., Napier, Johnathan, Vile, Denis, Domergue, F., Haslam, Richard, Napier, J. A., Bernard, Amélie, Sorel, Maud   +19 more
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Alzheimer's disease-like alterations in peripheral cells from presenilin-1 transgenic mice [PDF]

, 2006
Many cases of early-onset inherited Alzheimer's disease (AD) are caused by mutations in the presenilin-1 (PS1) gene. Expression of PS1 mutations in cell culture systems and in primary neurons from transgenic mice increases their vulnerability to cell ...
Czech, Christian, Schindowski, Katharina, Eckert, Anne, Leutner, Silke, Luckhaus, Christian, Touchet, Nathalie, Müller, Walter E.   +6 more
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