Results 211 to 220 of about 198,463 (306)

Phytochemicals and Health Benefits of American Ginseng (Panax quinquefolius L.): Current Knowledge and Future Perspectives

Food Safety and Health, EarlyView.
This review summarizes the chemical constituents and functional characteristics of American ginseng, aiming to provide references for its development and application. ABSTRACT American ginseng, a perennial herbaceous plant, is recognized for its significant medicinal properties and has attracted considerable attention due to its diverse phytochemical ...
Wei Geng, Ning Zhou, Jinqian Yu, Yanling Geng, Xiao Wang, Yannan Chen   +5 more
wiley   +1 more source

Mutant p53 Regulates Pyruvate Dehydrogenase Kinase 1 (PDK1) to Promote Proliferation and Migration in Breast Cancer. [PDF]

Cancer Sci
Ye Y, Ou Z, Li C, Liao Q, Zeng Q, Ju X, Zhang D, Wei Y, Zhang X, Zhang T, Wu K.   +10 more
europepmc   +1 more source

Greater Attention to Gingival Cancer and Floor of Mouth Cancer: Based on a Retrospective Analysis of Oral Cancer Across Different Subsites

Head &Neck, EarlyView.
ABSTRACT Background The gingiva and floor of the mouth are distinct subsites, and oral squamous cell carcinoma (OSCC) originating in these locations warrants further indepth understanding. Methods This study enrolled patients with OSCC from 2000 to 2020, and analyzed the clinicopathological characteristics.
Hao Li, Yi Ding, Yansheng Wu, Yan Fang, Xinhua Li, Weifeng Shi, Shaoshi Chen, Ailin Yang, Jin Zhang, Ruoyu Shi, Chao Jing, Xudong Wang, Yuansheng Duan   +12 more
wiley   +1 more source

Mutant p53 and chromatin regulation [PDF]

Nature, 2015
Carol Prives, Scott W. Lowe
openaire   +1 more source

Deceptive Thyroid Pathologies: Anaplastic Thyroid Carcinoma Mimics and Clinical Implications

Head &Neck, EarlyView.
ABSTRACT Background Beyond follicular‐derived thyroid carcinomas, lymphomas, and metastatic disease, there are rare pathologies of the thyroid gland that represent a challenge. We report patients with unusual malignancies that mimic similar aggressive cancers. Methods Retrospective case series.
David Z. Allen, S. Mohsen Hosseini, Mark Zafereo, Miriam Lango, Elizabeth Gardner Grubbs, Priyanka Iyer, Shreyaskumar R. Patel, Vinod Ravi, Naifa Lamki Busaidy, Rui Jennifer Wang, Michelle D. Williams, Maria E. Cabanillas, Anastasios Maniakas   +12 more
wiley   +1 more source

Novel p53 reactivators that are synergistic with olaparib for the treatment of gynecologic cancers with mutant p53. [PDF]

Transl Oncol
Smith LE, Padilla JL, Licor A, Steinkamp MP, Lagutina IV, Guo Y, Devor EJ, Pankratz VS, Sallmyr A, Oyebamiji OM, Choe JY, Williams GL, Leslie KK.   +12 more
europepmc   +1 more source

Mutant p53 Gain of Function: Why Many See It, Why Some Do Not. [PDF]

Cancer Discov
Lozano G, Prives C, Sabapathy K.
europepmc   +1 more source

Chemotherapy enhances HMGA1 secretion through the mutant p53-CK2 axis in pancreatic ductal adenocarcinoma cells. [PDF]

Cell Death Dis
Danzi F, Butera G, Sutton D, Perricone MD, Hu Y, Celesia A, Manfredi M, Brandi J, Pourmandi N, Nelson NS, Lin L, Bevere M, Pacchiana R, Pea A, Salvia R, Scarpa A, Luchini C, Cecconi D, Ugel S, Lyssiotis CA, Fiore A, Donadelli M.   +21 more
europepmc   +1 more source

Mutant p53 variants differentially impact replication initiation and activate cGAS-STING to affect immune checkpoint inhibition. [PDF]

Commun Biol
Liu K, Garan LAW, Lin FT, Lin WC.
europepmc   +1 more source

SMURF2 Facilitates GAP17 Isoform 1 Membrane Displacement to Promote Mutant p53-KRAS Oncogenic Synergy. [PDF]

Mol Cancer Res
Ray P, Shukla S, Zhang Y, Donahue KL, Nancarrow DJ, Kasturirangan S, Shankar S, Cuneo K, Thomas D, Gadgeel SM, Lawrence TS, Pasca di Magliano M, Ray D.   +12 more
europepmc   +1 more source