Results 1 to 10 of about 141,956 (266)

Mutation Analysis and Single Nucleotide Polymorphism (SNP) of TP53 in Breast CancerIn East Java [PDF]

Journal of Tropical Life Science, 2021
The Incidence of Indonesia breast cancer case in2018 was reportedat 20.7% or160,653 in number. The factors that caused breast cancer is TP53gene mutationand Single Nucleotide Polymorphism (SNP).
Rizqa Radhiyah, I Kade Karisma Gita Ardana, Wisnubroto, Dwi Listyorini, Hendra Susanto   +4 more
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Single-cell sequencing reveals the potential oncogenic expression atlas of human iPSC-derived cardiomyocytes

Biology Open, 2021
Human induced pluripotent stem cells (iPSCs) are important source for regenerative medicine. However, the links between pluripotency and oncogenic transformation raise safety issues.
Minglin Ou, Min Zhao, Chunhong Li, Donge Tang, Yong Xu, Weier Dai, Weiguo Sui, Yue Zhang, Zhen Xiang, Chune Mo, Hua Lin, Yong Dai   +11 more
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TP53 loss initiates chromosomal instability in fallopian tube epithelial cells

Disease Models & Mechanisms, 2021
High-grade serous ovarian cancer (HGSOC) originates in the fallopian tube epithelium and is characterized by ubiquitous TP53 mutation and extensive chromosomal instability (CIN).
Daniel Bronder, Anthony Tighe, Darawalee Wangsa, Dali Zong, Thomas J. Meyer, René Wardenaar, Paul Minshall, Daniela Hirsch, Kerstin Heselmeyer-Haddad, Louisa Nelson, Diana Spierings, Joanne C. McGrail, Maggie Cam, André Nussenzweig, Floris Foijer, Thomas Ried, Stephen S. Taylor   +16 more
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A study of the TP53 Germline Mutation and Clinicopathologic Features in Thai Children with Adrenocortical Carcinoma

Journal of Health Science and Medical Research (JHSMR), 2021
Objective: To determine the clinicopathologic features and germline tumor protein p53 (TP53) mutation in children with adrenocortical carcinoma (ACC). Material and Methods: This was a retrospective study.
Nadvadee Aungkawattanapong, Piti Techavichit, Supanun Lauhasurayotin, Kanhathai Chiengthong, Darintr Sosothikul, Chalinee Monsereenusorn, Vichit Supornsilchai, Kanya Suphapeetiporn, Chinachote Teerapakpinyo, Shanop Shuangshoti   +9 more
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Catching the driver mutations in Ewing sarcoma tumours: an in silico genomic analysis [PDF]

World Cancer Research Journal, 2019
OBJECTIVE: Ewing sarcoma (EWS) is a rare neuroectodermal-related malignancy affecting bones and soft tissues. The well-known hallmark of genomic alteration in EWS is gene fusion involving the Ewing Sarcoma Breakpoint Region 1 (EWSR1) gene.
E. Toraih, A. Toreih, M. Fawzy
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Age-related Variation in Expression of Breast Cancer Tumour Markers in Iranian Patients [PDF]

Middle East Journal of Cancer, 2021
Background: There are believed to be several risk factors affecting the prognosis of breast cancer through their effect on the growth rate of tumour.
Fatemeh Homaei Shandiz, Fahimeh Afzaljavan, Amir Tajbakhsh, Maryam Rivadeh, Nourieh Sharifi, Mohammad Taghi Shakeri, Alireza Pasdar   +6 more
doaj   +1 more source

Neural reprogramming via microRNAs: the new kid on the p53-deficient block

Molecular & Cellular Oncology, 2020
We recently reported a novel role for nerve-cancer crosstalk, demonstrating that tumor protein p53 (TP53) deficiency in head and neck squamous cell carcinoma leads to a decrease in miR-34a in tumor-shed vesicles. This directed sensory nerve reprogramming
Deborah A. Silverman, George A. Calin, Jeffrey N. Myers, Moran Amit   +3 more
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A Computational Model of Tumor Growth and Anakoinosis

Frontiers in Pharmacology, 2019
Anakoinosis is a new cancer treatment paradigm that posits a key role for communicative reprogramming within tumor systems. To date no mathematical or computational models of anakoinosis have been developed.
Pan Pantziarka, Pan Pantziarka, Lina Ghibelli, Albrecht Reichle   +3 more
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Disruption of tp53 leads to cutaneous nevus and melanoma formation in Xenopus tropicalis

Molecular Oncology, 2022
In humans, germline TP53 mutations predispose carriers to a wide spectrum of cancers, which is known as Li–Fraumeni syndrome (LFS). To date, the association of melanomas with LFS remains unestablished.
Rensen Ran, Lanxin Li, Zhaoying Shi, Guanghui Liu, Hao Jiang, Liangchen Fang, Tingting Xu, Jixuan Huang, Weiqi Chen, Yonglong Chen   +9 more
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Prognostic value of BCL2 and TP53 genetic alterations for diffuse large B-cell lymphoma patients treated with R-CHOP

Cancer Biology & Medicine, 2022
Objective: Limited data about the prognostic significance of BCL2 mutations and BCL2 copy number variations in diffuse large B-cell lymphoma (DLBCL) are available.
Yan Qin, Haizhu Chen, Peng Liu, Changgong Zhang, Jianliang Yang, Lin Gui, Xiaohui He, Liqiang Zhou, Shengyu Zhou, Shiyu Jiang, Hongxin Jiang, Yuankai Shi   +11 more
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