Results 1 to 10 of about 2,716,064 (346)

Review of the synthesis of semiconductor nanomaterials using ionizing radiation technology

open access: yesFushe yanjiu yu fushe gongyi xuebao, 2022
This work highlights the radiation-induced syntheses of numerous semiconductor nanomaterials, including metal oxides, metal sulfides, metal selenides, polymers, surface precious metal nanoparticles deposition, and vacancy-defect semiconductors.
ZHAO Caifeng   +11 more
doaj   +1 more source

A statistical framework for SNP calling, mutation discovery, association mapping and population genetical parameter estimation from sequencing data [PDF]

open access: yesBioinform., 2011
MOTIVATION Most existing methods for DNA sequence analysis rely on accurate sequences or genotypes. However, in applications of the next-generation sequencing (NGS), accurate genotypes may not be easily obtained (e.g. multi-sample low-coverage sequencing
Heng Li
semanticscholar   +1 more source

Bayesian networks elucidate complex genomic landscapes in cancer

open access: yesCommunications Biology, 2022
Bayesian network inference on several blood and solid cancer genomic datasets provides more accessible ways to explore driver events in cancer.
Nicos Angelopoulos   +4 more
doaj   +1 more source

Whole genome sequencing of Mycobacterium tuberculosis reveals slow growth and low mutation rates during latent infections in humans [PDF]

open access: yes, 2014
Very little is known about the growth and mutation rates of Mycobacterium tuberculosis during latent infection in humans. However, studies in rhesus macaques have suggested that latent infections have mutation rates that are higher than that observed ...
Alland, David   +9 more
core   +13 more sources

Inherited MUTYH mutations cause elevated somatic mutation rates and distinctive mutational signatures in normal human cells

open access: yesNature Communications, 2022
Inherited mutations in MUTYH have been shown to predispose patients to colorectal cancers. Here, the authors show that MUTYH mutations lead to an increased somatic base substitution mutation rate in normal intestinal epithelial cells, which is the likely
Philip S. Robinson   +25 more
doaj   +1 more source

MicroRNA-145 Impairs Classical Non-Homologous End-Joining in Response to Ionizing Radiation-Induced DNA Double-Strand Breaks via Targeting DNA-PKcs

open access: yesCells, 2022
DNA double-strand breaks (DSBs) are one of the most lethal types of DNA damage due to the fact that unrepaired or mis-repaired DSBs lead to genomic instability or chromosomal aberrations, thereby causing cell death or tumorigenesis.
Muddenahalli Srinivasa Sudhanva   +6 more
doaj   +1 more source

CtIP Regulates Mitotic Spindle Assembly by Modulating the TPX2-Aurora A Signaling Axis

open access: yesCells, 2022
CtBP-interacting protein (CtIP) plays a critical role in controlling the homologous recombination-mediated DNA double-stranded break (DSB) repair pathway through DNA end resection, and recent studies suggest that it also plays a role in mitosis. However,
Wonkyung Oh   +4 more
doaj   +1 more source

Quantitative assessments on induced high yielding mutant lines in urdbean [Vigna mungo (L.) hepper]

open access: yesLegume Science, 2022
Vigna mungo (L.) hepper is an important grain legume with immense potential for establishing food security worldwide. However, the low genetic variability due to the self‐pollination mode of reproduction restricts its improvement endeavours.
Sonu Goyal   +4 more
doaj   +1 more source

Field assessment of yield and its contributing traits in cowpea treated with lower, intermediate, and higher doses of gamma rays and sodium azide

open access: yesFrontiers in Plant Science, 2023
Across the globe, plant breeders of different organizations are working in collaboration to bring preferred traits to crops of economic importance. Among the traits, “high yielding potential” is the most important as it is directly associated with food ...
Aamir Raina, Aamir Raina, Samiullah Khan
doaj   +1 more source

Structural Insights into APOBEC3-Mediated Lentiviral Restriction

open access: yesViruses, 2020
Mammals have developed clever adaptive and innate immune defense mechanisms to protect against invading bacterial and viral pathogens. Human innate immunity is continuously evolving to expand the repertoire of restriction factors and one such family of ...
Krista A. Delviks-Frankenberry   +2 more
doaj   +1 more source

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