Results 21 to 30 of about 1,415,453 (269)
We used 60Co-γ ray and electron beam irradiation to mutate Bacillus velezensis to breed genetically stable mutant strains. The mutant strains were screened and re-screened by plate confrontation and the four-point method to study their antibacterial ...
XIE Hui +9 more
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The study investigated the chemical composition, supramolecular structures, particle size distribution, and enzymatic efficiency of Phragmites australis lignocelluloses (PALs) with different moisture contents and treatment with 5 MeV electron beam ...
CHEN Liang +7 more
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Estimating the Rate of Mutation to a Mutator Phenotype
A mutator is a variant in a population of organisms whose mutation rate is higher than the average mutation rate in the population. For genetic and population dynamics reasons, mutators are produced and survive with much greater frequency than anti-mutators (variants with a lower-than-average mutation rate).
Isaac Vázquez-Mendoza +4 more
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In this study, Triarrhena lutarioriparia was irradiated by a 5 MeV electron accelerator. The effects of temperature, formic acid concentration, and absorbed dose on the separation efficiency of cellulose from Triarrhena lutarioriparia were investigated ...
WANG Danyang +6 more
doaj +1 more source
Phenotypic diversity in mutagenized population of urdbean (Vigna mungo (L.) Hepper)
The present study was conducted to assess the extent of induced genetic variability and to determine the inheritance pattern of various yield contributing phenotypic traits in M2 and M3 generations of urdbean following mutagenesis with single and ...
Sonu Goyal +4 more
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Efficiency of carcinogenesis with and without a mutator mutation [PDF]
Carcinogenesis involves the acquisition of multiple genetic changes altering various cellular phenotypes. These changes occur within the fixed time period of a human lifespan, and mechanisms that accelerate this process are more likely to result in clinical cancers.
Robert A, Beckman, Lawrence A, Loeb
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Are Protein Shape-Encoded Lowest-Frequency Motions a Key Phenotype Selected by Evolution?
At the very deepest molecular level, the mechanisms of life depend on the operation of proteins, the so-called “workhorses” of the cell. Proteins are nanoscale machines that transform energy into useful cellular work, such as ion or nutrient transport ...
Laura Orellana
doaj +1 more source
Mutation Spectra and the Neutrality of Mutations [PDF]
The effect of amino acid replacements on enzyme function was studied in the tJ-galactosidase of Escherichia coli. Mutants possessing 50% or less of normal enzyme activity were isolated and examined. Of 733 amino acid substitutions calculated to have occurred, only 11 reduced tJ-galactosidase activity below 50 %.
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A spatial mutation model with increasing mutation rates
AbstractWe consider a spatial model of cancer in which cells are points on the d-dimensional torus $\mathcal{T}=[0,L]^d$ , and each cell with $k-1$ mutations acquires a kth mutation at rate $\mu_k$ . We assume that the mutation rates $\mu_k$ are increasing, and we find the asymptotic waiting time for the first cell to acquire k mutations as the ...
Brian Chao, Jason Schweinsberg
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