Results 201 to 210 of about 714,611 (262)

Associations of Age With Tumor Genomic Characteristics in Relapsed/Refractory Cancers Interrogated With the NCI-MATCH Trial Targeted Gene Panel Assay. [PDF]

JCO Precis Oncol
Sankaran H, Kotliarov Y, Zhao Y, Harris LN, Tricoli JV, Hamilton SR, Temkin SM, Karlovich C, Chang TC, Wang V, Gray RJ, Wei Z, Shin SJ, Seibel NL, Das B, Coffey B, Patton D, Li MC, Li J, Best AF, Williams PM, Iafrate AJ, Sklar J, Flaherty KT, Chen AP, O'Dwyer PJ, McShane LM.   +26 more
europepmc   +1 more source

Altered gene expression in the liver and small intestine of horses with equine neuroaxonal dystrophy

Equine Veterinary Journal, EarlyView.
Abstract Background Equine neuroaxonal dystrophy/degenerative myeloencephalopathy (eNAD/EDM) is the second most common diagnosis of spinal ataxia in horses in the United States. The disease develops due to a combination of vitamin E deficiency and an unknown genetic risk factor(s), and there currently is no effective treatment.
Stephanie Ryan, Blythe Durbin‐Johnson, Kevin Woolard, Andrew D. Miller, Carrie J. Finno   +4 more
wiley   +1 more source

Distinct mutational landscapes for germline and somatic cancer variants in forty tumor suppressor genes. [PDF]

Am J Hum Genet
Lulla SD, Ritter DI, Kesserwan C, Plon SE.   +3 more
europepmc   +1 more source

Neurolathyrism in Sub‐Saharan Africa—Assessing the Neurotoxic Risks of Lathyrus sativus Amid Drought and Food Security Challenges

Food Safety and Health, EarlyView.
Representation of grass pea consumption in drought‐stricken sub‐Saharan Africa sustains nutrition, but excess β‐ODAP exposure due to multiple reasons triggers neurolathyrism, a progressive neurotoxic disorder. ABSTRACT Neurolathyrism is a progressive motor neuron disease due to the consumption of Lathyrus sativus (grass pea) over long periods.
Biruk Demisse Ayalew, Muhammad Umar, Pakeezah Tabasum, Maria Qadri, Talha Farooq, Eskeatnaf Yosef Getachew, Zemichael Getu Alemayehu, Eden Haile Hagos, Hailemariam Shimelis Gebeyehu, Hanna Tsehay Abebe, Nuradin Abdi Ali, David Chinaecherem Innocent, Temesgen Mamo Sharew   +12 more
wiley   +1 more source

Synergistic role of molecular imaging and genomics in thyroid cancer management: from diagnosis to personalized treatment. [PDF]

J Transl Med
Ahmadi S, Hoseini M, Ravari MS, Zarei M, Shahrokhi P, Mousavi P.   +5 more
europepmc   +1 more source

Electrostatics and disease: Large-scale assessment of human missense variants causing protein charge alterations and their implications for disease. [PDF]

Biophys J
Modha N, Panday SK, Alexov E.
europepmc   +1 more source

<i>In silico</i> protein structure analysis of nine deleterious <i>NIT1</i> missense mutations identified in human cancers. [PDF]

MicroPubl Biol
Parajuli A, Phan H, Walsh S.
europepmc   +1 more source

Gene signatures characterizing driver mutations in lung squamous carcinoma are predictive of the progression of pre‐cancer lesions

International Journal of Cancer, EarlyView.
What's New? Lung squamous cell carcinoma (LUSC) is more aggressive than lung adenocarcinoma, and is most often diagnosed at an advanced stage. Here, the authors evaluated gene expression data from LUSC tumors and came up with gene signatures for 34 genetic abnormalities whose expression changes throughout different precancerous stages. Several of these
Yupei Lin, Venugopalareddy Mekala, Jianrong Li, Xiang Wang, Muhammad Aminu, Jia Wu, Jianjun Zhang, Robert Taylor Ripley, Christopher I. Amos, Chao Cheng   +9 more
wiley   +1 more source

Decoding cancer-associated ribosomal protein mutations: A new frontier in cancer and ribosome biology. [PDF]

Hemasphere
Čaušević M, Loewith R, Volarević S.
europepmc   +1 more source