Results 231 to 240 of about 4,183,748 (324)

Cancer--A Biological Approach: I. The Processes Of Control. II. The Significance of Somatic Mutation [PDF]

, 1957
Michael Burnet
openalex   +1 more source

Novel compound heterozygous mutation in <i>DNAH9</i> causes complex congenital heart disease. [PDF]

Mol Med Rep
Liu X, Zhou JL, Yang CY, Zhou HY, He WB, Yang J.   +5 more
europepmc   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

Some Remarks on Mr. Kunhi Kannan's Paper, “An Instance of Mutation.”

, 1918
E. Ernest Green
openalex   +2 more sources

High resolution clonal architecture of hypomutated Wilms tumours. [PDF]

Nat Commun
Lee-Six H, Treger TD, Dave M, Coorens TH, Anderson ND, Tiersma Y, Derakhshan S, de Haan S, van den Heuvel-Eibrink MM, Wang Y, Wenger A, Al-Saadi R, Lawford A, Letunovska A, Wegert J, Parks C, Morcrette G, Gessler M, Vujanic G, Chowdhury T, J O'Sullivan M, de Krijger RR, Stratton MR, Pritchard-Jones K, Hutchinson JC, Drost J, Behjati S.   +26 more
europepmc   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

Cancer Immunotherapy Based on Mutation-Specific CD4+ T Cells in a Patient with Epithelial Cancer

Science, 2014
E. Tran, S. Turcotte, A. Gros, P. Robbins, Yong-Chen Lu, M. Dudley, J. Wunderlich, R. Somerville, Katherine A. Hogan, C. Hinrichs, M. Parkhurst, J. Yang, S. Rosenberg   +12 more
semanticscholar   +1 more source

Species and Varieties, Their Origin by Mutation.

, 1905
Huw Richards, Hugo de Vries, D. T. MacDougal   +2 more
openalex   +3 more sources

Association of TERT promoter mutation with oral squamous cell carcinoma: a systematic review and meta-analysis. [PDF]

Sci Rep
Yuwanati M, Sarode S, Sarode G, Gadbail A, Gondivkar S, Chaurasia A, Dwivedi D, Delgadillo-Barrera S.   +7 more
europepmc   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source