Results 81 to 90 of about 2,716,384 (302)

Model Driven Mutation Applied to Adaptative Systems Testing [PDF]

, 2011
Dynamically Adaptive Systems modify their behav- ior and structure in response to changes in their surrounding environment and according to an adaptation logic. Critical sys- tems increasingly incorporate dynamic adaptation capabilities; examples include
Bartel, Alexandre, Baudry, Benoit, Klein, Jacques, Mouelhi, Tejeddine, Munoz, Freddy, Traon, Yves Le   +5 more
core   +4 more sources

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

Three distinct hematological malignancies from a single germ cell tumor: a case report

Journal of Medical Case Reports, 2020
Background The association between non seminomatous germ cell tumors (GCTs) and hematological malignancies of rare lineage has been described in the literature.
M. Spencer Chapman, P. C. May, E. Olavarria, E. Nadal Melsio   +3 more
doaj   +1 more source

Monotonicity of Fitness Landscapes and Mutation Rate Control [PDF]

, 2016
A common view in evolutionary biology is that mutation rates are minimised. However, studies in combinatorial optimisation and search have shown a clear advantage of using variable mutation rates as a control parameter to optimise the performance of ...
A Kong, AE Eiben, AE Nix, AF Agrawal, AF Agrawal, Alastair Channon, BMR Stadler, CA Aktipis, CA Aktipis, CG Knight, Christopher G. Knight, DR Rokyta, Elizabeth Aston, FC Adams, G Badis, HA Orr, HA Orr, HA Orr, HA Orr, HA Orr, I Bjedov, ID Falco, J Cervantes, J He, JA Visser de, JM Smith, John Aston, L Hadany, M Kimura, MJ McDonald, O Tenaillon, P Schuster, R Ahlswede, R Kassen, R Krašovec, R Poli, RA Fisher, RC MacLean, RJ Woods, Rok Krašovec, Roman V. Belavkin, RS Galhardo, S Banach, S Böttcher, S Collins, S Mazurkiewicz, SJ Freeland, T Bataillon, T Jansen, V Mustonen, WH Zhong, Y Ram   +51 more
core   +4 more sources

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source

This Is Not a Myeloproliferative Neoplasm…

Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
wiley   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Adaptive group mutation for tackling deception in genetic search [PDF]

, 2004
Copyright @ 2004 WSEASIn order to study the efficacy of genetic algorithms (GAs), a number of fitness landscapes have been designed and used as test functions.
Yang, S
core  

Opposition based Ensemble Micro Differential Evolution

, 2017
Differential evolution (DE) algorithm with a small population size is called Micro-DE (MDE). A small population size decreases the computational complexity but also reduces the exploration ability of DE by limiting the population diversity. In this paper,
Rahnamayan, Shahryar, Salehinejad, Hojjat, Tizhoosh, Hamid R.   +2 more
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source