Results 61 to 70 of about 1,981,585 (256)

Gamma rays and sodium azide induced variations in bio-physiological and agronomical traits in linseed (Linum usitatissimum L.)

open access: yesHeliyon
Linseed is a valuable oilseed crop with huge therapeutic importance due to its high content of omega-3 fatty acids in the form of Alpha-linolenic acid (ALA).
Roshan Jahan   +3 more
doaj   +1 more source

Comparative effects of caffeine and lead nitrate on the bio-physiological and yield associated traits of lentil (Lens culinaris Medik.)

open access: yesHeliyon, 2023
Lentil belonging to the fabaceae family is a proteinaceous cool-season legume consumed across the world. However, lentil is low yielding with a narrow genetic base compared to other grain legumes such as chickpea, faba bean, and cowpea.
Janib Yousuf   +4 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Mechanisms of Genome Maintenance in Plants: Playing It Safe With Breaks and Bumps

open access: yesFrontiers in Genetics, 2021
Maintenance of genomic integrity is critical for the perpetuation of all forms of life including humans. Living organisms are constantly exposed to stress from internal metabolic processes and external environmental sources causing damage to the DNA ...
Aamir Raina   +7 more
doaj   +1 more source

Mutation testing from probabilistic and stochastic finite state machines [PDF]

open access: yes, 2009
Specification mutation involves mutating a specification, and for each mutation a test is derived that distinguishes the behaviours of the mutated and original specifications. This approach has been applied with finite state machine based models.
García Merayo, María De Las Mercedes   +3 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gamma Rays and Sodium Azide Induced Genetic Variability in High-Yielding and Biofortified Mutant Lines in Cowpea [Vigna unguiculata (L.) Walp.]

open access: yesFrontiers in Plant Science, 2022
With the twin pressures of high population growth and extreme weather events, developing countries are the worst hit in meeting the food demands of their people, with millions unable to access adequate and nutritionally balanced food.
Aamir Raina   +6 more
doaj   +1 more source

KRAS mutation analysis by PCR : a comparison of two methods [PDF]

open access: yes, 2015
Background: KRAS mutation assays are important companion diagnostic tests to guide anti-EGFR antibody treatment of metastatic colorectal cancer. Direct comparison of newer diagnostic methods with existing methods is an important part of validation of ...
Lucas, Katie   +9 more
core   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Self-adaptation of mutation distribution in evolution strategies for dynamic optimization problems [PDF]

open access: yes, 2011
Copyright @ IOS Press. All Rights Reserved.Evolution strategies with q-Gaussian mutation, which allows the self-adaptation of the mutation distribution shape, is proposed for dynamic optimization problems in this paper.
Yang, S, Yang, Shengxiang, Tinós, R
core   +1 more source

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