Results 51 to 60 of about 2,716,384 (302)

Genomic landscape and chronological reconstruction of driver events in multiple myeloma

Nature Communications, 2019
Multiple myeloma evolves continuously. Here the authors chronologically reconstruct driver events in multiple myeloma, noting a limited repertoire of initiating driver events that shape the evolutionary trajectory of the disease.
Francesco Maura, Niccoló Bolli, Nicos Angelopoulos, Kevin J. Dawson, Daniel Leongamornlert, Inigo Martincorena, Thomas J. Mitchell, Anthony Fullam, Santiago Gonzalez, Raphael Szalat, Federico Abascal, Bernardo Rodriguez-Martin, Mehmet Kemal Samur, Dominik Glodzik, Marco Roncador, Mariateresa Fulciniti, Yu Tzu Tai, Stephane Minvielle, Florence Magrangeas, Philippe Moreau, Paolo Corradini, Kenneth C. Anderson, Jose M. C. Tubio, David C. Wedge, Moritz Gerstung, Hervé Avet-Loiseau, Nikhil Munshi, Peter J. Campbell   +27 more
doaj   +1 more source

MUTATION AND SELECTION [PDF]

Science, 1904
n ...
openaire   +2 more sources

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine, Ofélie Trudeau‐Ferrin, Caroline Laverdière, Patrick Hamel, Rosanne Superstein, Bénédicte Koukoui, Carole Provost, Paul C. Nathan, Vijay Ramaswamy, Furqan Shaikh, Brenda Gallie, Ashwin Mallipatna, Stephanie Kletke, Helen Dimaras, Hallie Coltin   +14 more
wiley   +1 more source

Author Correction: A practical guide for mutational signature analysis in hematological malignancies

Nature Communications, 2019
An amendment to this paper has been published and can be accessed via a link at the top of the ...
Francesco Maura, Andrea Degasperi, Ferran Nadeu, Daniel Leongamornlert, Helen Davies, Luiza Moore, Romina Royo, Bachisio Ziccheddu, Xose S. Puente, Herve Avet-Loiseau, Peter J. Campbell, Serena Nik-Zainal, Elias Campo, Nikhil Munshi, Niccolò Bolli   +14 more
doaj   +1 more source

Comparative effects of caffeine and lead nitrate on the bio-physiological and yield associated traits of lentil (Lens culinaris Medik.)

Heliyon, 2023
Lentil belonging to the fabaceae family is a proteinaceous cool-season legume consumed across the world. However, lentil is low yielding with a narrow genetic base compared to other grain legumes such as chickpea, faba bean, and cowpea.
Janib Yousuf, Aamir Raina, Shiekh Rasik, Zubair Altaf Reshi, Durre Shahwar   +4 more
doaj   +1 more source

Efficient sampling of large-scale transition pathways and intermediate conformations in sub-mesoscopic protein complexes

Nature Communications
Protein conformational changes are the cornerstone of biological function. While conformers captured experimentally represent metastable states, the pathways connecting them have been elusive for experiments and simulations alike.
Domenico Scaramozzino, Byung Ho Lee, Laura Orellana   +2 more
doaj   +1 more source

Mechanisms of Genome Maintenance in Plants: Playing It Safe With Breaks and Bumps

Frontiers in Genetics, 2021
Maintenance of genomic integrity is critical for the perpetuation of all forms of life including humans. Living organisms are constantly exposed to stress from internal metabolic processes and external environmental sources causing damage to the DNA ...
Aamir Raina, Aamir Raina, Parmeshwar K. Sahu, Rafiul Amin Laskar, Nitika Rajora, Richa Sao, Samiullah Khan, Rais A. Ganai   +7 more
doaj   +1 more source

An adaptive mutation operator for particle swarm optimization [PDF]

, 2008
Copyright @ 2008 MICParticle swarm optimization (PSO) is an effcient tool for optimization and search problems. However, it is easy to betrapped into local optima due to its in-formation sharing mechanism.
Korejo, I, Li, C, Yang, S
core  

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Gamma rays and sodium azide induced variations in bio-physiological and agronomical traits in linseed (Linum usitatissimum L.)

Heliyon
Linseed is a valuable oilseed crop with huge therapeutic importance due to its high content of omega-3 fatty acids in the form of Alpha-linolenic acid (ALA).
Roshan Jahan, Aamir Raina, Saima Malik, Samiullah Khan   +3 more
doaj   +1 more source