Results 51 to 60 of about 1,981,585 (256)

Evolution strategies with q-Gaussian mutation for dynamic optimization problems [PDF]

, 2010
This article is posted here with permmission from IEEE - Copyright @ 2010 IEEEEvolution strategies with q-Gaussian mutation, which allows the self-adaptation of the mutation distribution shape, is proposed for dynamic optimization problems in this paper.
Yang, S, Tinos, Renato, Tinos, R, null Shengxiang Yang, Renato Tino, Yang, Shengxiang   +5 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Abstention électorale à Madagascar : entre déficit civique et défaillance de la classe politique [PDF]

Mouvements et Enjeux Sociaux, 2022
Longtemps ignorée par les chercheurs en sciences sociales, l’abstention électorale devient une des problématiques majeures de la démocratie représentative en ce moment. Tel est également le cas pour Madagascar.
Jean Angelson RANDRIAMBOAVONJY
doaj  

Mutation testing from probabilistic finite state machines [PDF]

, 2007
Mutation testing traditionally involves mutating a program in order to produce a set of mutants and using these mutants in order to either estimate the effectiveness of a test suite or to drive test generation.
Robert M. Hierons, Mercedes G. Merayo, Hierons, RM, Merayo, MG   +3 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Efficient sampling of large-scale transition pathways and intermediate conformations in sub-mesoscopic protein complexes

Nature Communications
Protein conformational changes are the cornerstone of biological function. While conformers captured experimentally represent metastable states, the pathways connecting them have been elusive for experiments and simulations alike.
Domenico Scaramozzino, Byung Ho Lee, Laura Orellana   +2 more
doaj   +1 more source

Author Correction: A practical guide for mutational signature analysis in hematological malignancies

Nature Communications, 2019
An amendment to this paper has been published and can be accessed via a link at the top of the ...
Francesco Maura, Andrea Degasperi, Ferran Nadeu, Daniel Leongamornlert, Helen Davies, Luiza Moore, Romina Royo, Bachisio Ziccheddu, Xose S. Puente, Herve Avet-Loiseau, Peter J. Campbell, Serena Nik-Zainal, Elias Campo, Nikhil Munshi, Niccolò Bolli   +14 more
doaj   +1 more source

Comparative Mutagenic Effectiveness and Efficiency of Gamma Rays and Sodium Azide in Inducing Chlorophyll and Morphological Mutants of Cowpea

Plants, 2022
Mutagenic effectiveness and efficiency are the most important factors determining the success of mutation breeding, a coherent tool for quickly enhancing genetic diversity in crops. However, conclusive evidence of using an effective and efficient dose of
Aamir Raina, Rafiul Amin Laskar, Mohammad Rafiq Wani, Basit Latief Jan, Sajad Ali, Samiullah Khan   +5 more
doaj   +1 more source

Semantically Driven Mutation in Genetic Programming [PDF]

, 2008
Using semantic analysis, we present a technique known as semantically driven mutation which can explicitly detect and apply behavioural changes caused by the syntactic changes in programs that result from the mutation operation. Using semantically driven
Beadle, Lawrence, Colin G. Johnson, Johnson, Colin G., Lawrence Beadle   +3 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source