Results 81 to 90 of about 2,822,760 (305)
Acta Odontologica ScandinavicaObjective: Smokeless tobacco has been linked to the genetic modification of oral squamous cell carcinoma (OSCC). Our study aims to further investigate the disease among Naswar users at the genomic level to understand genetic diversity and discover new ...
Fatima Iqbal +3 more
doaj +1 more source
Molecular Deregulation of EPAS1 in the Pathogenesis of Esophageal Squamous Cell Carcinoma
Frontiers in Oncology, 2020 Endothelial PAS domain-containing protein 1 (EPAS1) is an angiogenic factor and its implications have been reported in many cancers but not in esophageal squamous cell carcinoma (ESCC).
Farhadul Islam +5 more
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
El conjunto habitacional Las Américas, un laboratorio para la edificación de una microsociedad
Alteridades, 2014 En un reciente conjunto habitacional de interés social ubicado en Ecatepec, Estado de México, se observan condiciones de vida y patrones de movilidad e inmovilidad que generan cierto aislamiento de sus residentes, haciendo de éste un territorio de vida ...
Céline Jacquin
doaj
A non-invasive method for screening mitochondrial diabetes
Frontiers in GeneticsBackgroundMitochondrial diabetes mellitus (MDM) is a special type of diabetes resulting from functional defects in mitochondria. Its incidence rate is low, and it can often be misdiagnosed as either type 1 or type 2 diabetes in clinical settings.
Hangyu Fang +12 more
doaj +1 more source
Mutation timing in a spatial model of evolution [PDF]
, 2020 Motivated by models of cancer formation in which cells need to acquire $k$ mutations to become cancerous, we consider a spatial population model in which the population is represented by the $d$-dimensional torus of side length $L$.
Foo, Jasmine +2 more
core +2 more sources
Frequency and significance of Ras, Tert promoter, and Braf mutations in cytologically indeterminate thyroid nodules: A monocentric case series at a tertiary-level Endocrinology unit [PDF]
, 2017 PurposeThe management of thyroid nodules of indeterminate cytology is controversial. Our study aimed to establish the frequency and significance of H-,K-,N-RAS, TERT promoter, and BRAF gene mutations in thyroid nodes of indeterminate cytology and to ...
Barollo, Susi +13 more
core +2 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Alʹmanah Kliničeskoj Mediciny, 2019 Rationale: Cystic fibrosis (CF; OMIM 219700) is a common hereditary disease caused by mutations in the CFTR gene (OMIM 602421). The distribution and frequencies of the CFTR gene mutations vary considerably between countries and ethnic groups.
N. V. Petrova +11 more
doaj +1 more source
Spontaneous phenotypic suppression of GacA-defective Vibrio fischeri is achieved via mutation of csrA and ihfA [PDF]
, 2015 Background: Symbiosis defective GacA-mutant derivatives of Vibrio fischeri are growth impaired thereby creating a selective advantage for growth-enhanced spontaneous suppressors. Suppressors were isolated and characterized for effects of the mutations on
Avitabile, Ashley +3 more
core +1 more source