Results 81 to 90 of about 3,248,558 (306)
Un point de vue néoréaliste en épistémologie du journalisme
Sur le Journalisme, 2017 Il peut y avoir un certain intérêt à traiter de la nature du journalisme non pas pour en circonscrire les limites, mais afin de mettre au jour les présuppositions qui président à sa pratique. C’est une proposition en ce sens qui est ici formulée.
Gilles Gauthier
doaj
Acta Odontologica ScandinavicaObjective: Smokeless tobacco has been linked to the genetic modification of oral squamous cell carcinoma (OSCC). Our study aims to further investigate the disease among Naswar users at the genomic level to understand genetic diversity and discover new ...
Fatima Iqbal +3 more
doaj +1 more source
Molecular Deregulation of EPAS1 in the Pathogenesis of Esophageal Squamous Cell Carcinoma
Frontiers in Oncology, 2020 Endothelial PAS domain-containing protein 1 (EPAS1) is an angiogenic factor and its implications have been reported in many cancers but not in esophageal squamous cell carcinoma (ESCC).
Farhadul Islam +5 more
doaj +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
El conjunto habitacional Las Américas, un laboratorio para la edificación de una microsociedad
Alteridades, 2014 En un reciente conjunto habitacional de interés social ubicado en Ecatepec, Estado de México, se observan condiciones de vida y patrones de movilidad e inmovilidad que generan cierto aislamiento de sus residentes, haciendo de éste un territorio de vida ...
Céline Jacquin
doaj
A non-invasive method for screening mitochondrial diabetes
Frontiers in GeneticsBackgroundMitochondrial diabetes mellitus (MDM) is a special type of diabetes resulting from functional defects in mitochondria. Its incidence rate is low, and it can often be misdiagnosed as either type 1 or type 2 diabetes in clinical settings.
Hangyu Fang +12 more
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Alʹmanah Kliničeskoj Mediciny, 2019 Rationale: Cystic fibrosis (CF; OMIM 219700) is a common hereditary disease caused by mutations in the CFTR gene (OMIM 602421). The distribution and frequencies of the CFTR gene mutations vary considerably between countries and ethnic groups.
N. V. Petrova +11 more
doaj +1 more source
Adaptation to high ethanol reveals complex evolutionary pathways [PDF]
, 2015 Tolerance to high levels of ethanol is an ecologically and industrially relevant phenotype of microbes, but the molecular mechanisms underlying this complex trait remain largely unknown.
Arslan, Ahmed +15 more
core +4 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source