The leukemia-associated RUNX1/ETO oncoprotein confers a mutator phenotype. [PDF]
Leukemia, 2016 Forster VJ +10 more
europepmc +1 more source
Phenotypic Heterogeneity of the m.14459G>A Mutation [PDF]
Child Neurology Open, 2017 Finsterer, Josef, Zarrouk-Mahjoub, Sinda
openaire +2 more sources
Mutator Phenotype and DNA Double-Strand Break Repair in BLM Helicase-Deficient Human Cells. [PDF]
Mol Cell Biol, 2016 Suzuki T, Yasui M, Honma M.
europepmc +1 more source
The “Aneuploidy–Modified Mutator-Phenotype” Theory of Malignant Tumors
Cellular Oncology, 2008 Leon P. Bignold
doaj +1 more source
CHARACTERIZATION OF CONTINUOUS DELIVERY OF BDNF ON DENTATE GYRUS NEUROGENESIS IN POL G MUTATOR MICE
, 2015 Polymerase gamma POL G1 mutator mice (POL G) are deficient in the mitochondrial DNA proof-reading capacity leading to an accumulation of mtDNA point mutations, resulting in accelerated aging phenotype and brain atrophy.
Gomez-Vargas, Andrew
core
Nucleotide selectivity defect and mutator phenotype conferred by a colon cancer-associated DNA polymerase δ mutation in human cells. [PDF]
Oncogene, 2017 Mertz TM +4 more
europepmc +1 more source
, 2008 dissertationThe overall god of this dissertation is to investigate the role of specific biochemical determinants of DNA replication fidelity in genomic stability and tumor progression in mammals.
Singh, Mallika.
core
The Polg Mutator Phenotype Does Not Cause Dopaminergic Neurodegeneration in DJ-1-Deficient Mice. [PDF]
eNeuro, 2015 Hauser DN +4 more
europepmc +1 more source
Cancer. Aneuploidy drives a mutator phenotype in cancer. [PDF]
Science, 2011 Kolodner RD, Cleveland DW, Putnam CD.
europepmc +1 more source
Lethal mutagenesis: targeting the mutator phenotype in cancer. [PDF]
Semin Cancer Biol, 2010 Fox EJ, Loeb LA.
europepmc +1 more source