Results 31 to 40 of about 35,876 (250)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Coupling coordination between higher education and environmental governance: Evidence of western China

PLoS ONE, 2022
Exploring the coupling coordination mechanism between higher education and environmental governance is conducive to understanding the mutual interactions between them and thus enhancing mutual development.
Yuqing Geng, Fuchang Huang
doaj   +3 more sources

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

The Mitigation of Mutual Coupling Effects in Multi-Beam Echosounder Calibration under Near-Field Conditions

Journal of Marine Science and Engineering
The advancement of unmanned platforms is driving the miniaturization and cost reduction of the multi-beam echosounder (MBES). In the process of MBES array calibration, the mutual coupling significantly impacts the performance of parameter estimation.
Wanyuan Zhang, Weijia Yuan, Gongwu Sun, Tengjiao He, Junqi Qu, Chao Xu   +5 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Classification and Localization of Mixed Sources after Blind Calibration of Unknown Mutual Coupling

International Journal of Antennas and Propagation, 2019
In order to deal with the problem of passive mixed source localization under unknown mutual coupling, the authors propose an effective algorithm. This algorithm provides array blind calibration as well as classification and localization of mixed sources ...
Kai Wang, Ling Wang, Jian Xie, Yuexian Wang   +3 more
doaj   +1 more source

Sparse Bayesian Learning Based Space-Time Adaptive Processing Against Unknown Mutual Coupling for Airborne Radar Using Middle Subarray

IEEE Access, 2019
Sparse-recovery-based space–time adaptive processing (STAP) methods can exhibit superior clutter suppression performance with limited training data.
Zhihui Li, Yiduo Guo, Yongshun Zhang, Hao Zhou, Guimei Zheng   +4 more
doaj   +1 more source

Electromagnetic machine learning for estimation and mitigation of mutual coupling in strongly coupled arrays

ICT Express, 2023
With the recent advancement in baseband integrated circuits and radio frequency (RF) technology, there is a strong demand to minimize the size of array-based microwave systems. However, array aperture miniaturization often leads to strong mutual coupling
Oluwole John Famoriji, Thokozani Shongwe
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source