Results 61 to 70 of about 1,573,620 (330)

Mutual Exclusion Statistics in Exactly Solvable Models in One and Higher Dimensions at Low Temperatures

open access: yes, 1996
We study statistical characterization of the many-body states in exactly solvable models with internal degrees of freedom. The models under consideration include the isotropic and anisotropic Heisenberg spin chain, the Hubbard chain, and a model in ...
B. I. Halperin   +51 more
core   +2 more sources

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Brief Announcement: Neighborhood Mutual Remainder and Its Self-Stabilizing Implementation of Look-Compute-Move Robots [PDF]

open access: yes, 2019
In this paper, we define a new concept neighborhood mutual remainder (NMR). An NMR distributed algorithms should satisfy global fairness, l-exclusion and repeated local rendezvous requirements.
Dolev, Shlomi   +4 more
core   +1 more source

Tournaments for mutual exclusion: verification and concurrent complexity

open access: yesFormal Aspects of Computing, 2017
Given a mutual exclusion algorithm MXd for $${d \geq 2}$$d≥2 threads, a mutual exclusion algorithm for $${N > d}$$N>d threads can be built in a tree of degree d with N leaves, with the critical section at the root of the tree.
W. Hesselink
semanticscholar   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

A minimal model for multiple epidemics and immunity spreading. [PDF]

open access: yesPLoS ONE, 2010
Pathogens and parasites are ubiquitous in the living world, being limited only by availability of suitable hosts. The ability to transmit a particular disease depends on competing infections as well as on the status of host immunity.
Kim Sneppen   +3 more
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

open access: yesFEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

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