Results 161 to 170 of about 488,983 (281)

Adaptation of a mutual exclusivity framework to identify driver mutations within oncogenic pathways. [PDF]

Am J Hum Genet
Wang X, Kostrzewa C, Reiner A, Shen R, Begg C.   +4 more
europepmc   +1 more source

Tendency-driven Mutual Exclusivity for Weakly Supervised Incremental Semantic Segmentation [PDF]

Weakly Incremental Learning for Semantic Segmentation (WILSS) leverages a pre-trained segmentation model to segment new classes using cost-effective and readily available image-level labels. A prevailing way to solve WILSS is the generation of seed areas
Yang, Xiaokang, Shen, Wei, Si, Chongjie, Wang, Xuehui   +3 more
core  

Bone Marrow Macrophage STING Signaling is a Direct Nexus Linking Marrow Adipose Expansion to NAD+ Depletion and Osteogenic Decline in Skeletal Aging

Advanced Science, EarlyView.
This study reveals that during skeletal aging, bone marrow adipocyte‐derived sDPP4 primes STING signaling in macrophages. In combination with mitochondrial DNA, this signaling activates CD38 and depletes local NAD+/NMN, thereby impairing osteogenesis.
Zhichao Li, Kuanhui Gao, Mengjie Wang, Songlin Liang, Dandan Li, Guoqing Tan, Haipeng Xue, Yujie Liu, Peng Zhang, Zhanwang Xu, Wenxiang Cheng, Yongjun Wang, Nianhu Li   +12 more
wiley   +1 more source

Mutual exclusivity and co-occurrence patterns of immune checkpoints indicate NKG2A relates to anti-PD-1 resistance in gastric cancer. [PDF]

J Transl Med
Li G, Liu X, Gu C, Ma G, Li S, Ma Z, Xiong Y, Jiang Y, Huang Q, Wu J, Wu Z, Liao W, Wu Q, Shi M.   +13 more
europepmc   +1 more source

Access to Audio-visual Contents, Exclusivity and Anticommons in New Media Markets [PDF]

Media markets are characterized by strong peculiarities that often call for longterm exclusivity contracts between content providers and distributors or for vertical or horizontal integration.
Maria Alessandra ROSSI, Antonio NICITA
core  

Phase Separation of SF3B1 Serves as a Critical Post‐Transcriptional Regulator During Early Mouse Embryogenesis

Advanced Science, EarlyView.
Phase separation of SF3B1 acts as a key regulatory mechanism for dynamic alternative splicing throughout early mouse embryogenesis. Its absence triggers extensive splicing errors, which induce persistent DNA damage, defective cell cycle progression, and failed cell lineage commitment, and ultimately hinder the normal growth and development of ...
Kang Zhao, Ting‐Yu Han, Yan‐Li Cheng, Yi‐Dan Zhang, Yu‐Wei Zhang, JinJian Guo, ShaoJun Zhang, WenZe Huang, Jing Zhang, Pei‐Yu Liao, Ying Xin, ChuanChen Chu, Qing‐Yuan Sun, ZhiZhen Liu, Xiang‐Hong Ou, Jun Xie   +15 more
wiley   +1 more source

WeSME: uncovering mutual exclusivity of cancer drivers and beyond. [PDF]

Bioinformatics, 2017
Kim YA, Madan S, Przytycka TM.
europepmc   +1 more source

Vertical Integration, Exclusivity and Game Sales Performance in the U.S. Video Game Industry [PDF]

This paper empirically investigates the relation between vertical integration and video game performance in the U.S. video game industry. For this purpose, we use a widely used data set from NPD on video game montly sales from October 2000 to October ...
Warzynski, Frédéric, Gil, Ricard
core  

Abstract Representation of Movement Parameters in Basal Ganglia Output

Advanced Science, EarlyView.
The basal ganglia output provides a scalable velocity/position signal across behavioral contexts, supporting the idea that these variables are represented in the brain as abstract entities rather than as fixed changes in joint angles or specific sets of body effectors.
Ana Silvia Báez‐Cordero, Diana I. Ortega‐Romero, Claudia I. Pérez‐Díaz, Pavel E. Rueda‐Orozco   +3 more
wiley   +1 more source

Harnessing mutual exclusivity between TP53 and ARID1 A mutations. [PDF]

Cell Cycle, 2017
Wu S, Fatkhutdinov N, Zhang R.
europepmc   +1 more source