Results 221 to 230 of about 488,983 (281)

Genomic landscape and clinical characteristics of ERBB2/HER2-mutated colorectal cancers. [PDF]

Oncologist
Aksu MD, Peniche PZ, Baytar DK, Jambunathan B, Jan YJA, Hsieh R, Rahman S, Krauss JC, Veenstra CM, Sahin IH.   +9 more
europepmc   +1 more source

Mechanical Distraction Engages a Neuro‐Immune Program to Drive Regenerative Soft‐Tissue Healing in Ilizarov Bone Transport

Advanced Science, EarlyView.
Ilizarov bone transport accelerates healing of soft‐tissue wounds through unclear mechanisms. In a rat model, sustained mechanical distraction elicits calcitonin gene‐related peptide (CGRP)‐dominant sensory reinnervation, creating a niche that shifts immune cells from inflammatory to repair‐promoting states and speeds re‐epithelialization.
Yueliang Zhu, Jiayu Chen, Xuehuan Wen, Kaijia Tang, Ling Gao, Chenxing Wang, Yixuan Feng, Si‐He Qin, Tao Chen, Xiaohua Yu   +9 more
wiley   +1 more source

From Artificial to Embodied and Physical Intelligence in Smart Manufacturing

Advanced Science, EarlyView.
Smart manufacturing is reframed through complementary artificial, embodied, and physical intelligence, spanning computational reasoning, perception‐action coupling, and material‐level adaptation. Their integration across design, fabrication, operation, and maintenance reveals how intelligence can be co‐designed across algorithms, embodied agents, and ...
Kang Wang, Xinyu Lu, Tong Liu, Jinjie Fang, Xin Li, Siqian Wu, Liuchao Jin, Wei‐Hsin Liao, Shuyou Zhang, Jianrong Tan   +9 more
wiley   +1 more source

Genomic Determinants of Induction Failure and Persistent Prognostic Risk of <i>FLT3</i>-ITD in Pediatric Acute Myeloid Leukemia. [PDF]

Cancers (Basel)
Liu R, Cui Y, Huang L, Guan X, Shen Y, Dou Y, Wen X, Guo Y, Liu H, Yao X, Xiang Y, Zeng X, Liu Q, Yu J.   +13 more
europepmc   +1 more source

Metasurface‐Based Multidimensional Light‐Field Manipulation: From Technologies to Applications

Advanced Science, EarlyView.
Multidimensional metasurfaces enable versatile manipulation of multiple optical degrees of freedom, including phase, amplitude, polarization, wavelength, and orbital angular momentum. This review summarizes their fundamental mechanisms, emerging strategies for multidimensional light‐field control, and key applications in optical computing, imaging ...
Heliang Yin, Shuo Sun, Jiahao Zhang, Jianuo Hu, Yubin Qiao, Liang Chen, Jin Li   +6 more
wiley   +1 more source

An Integrated Framework Coupling Hierarchical Hyperspectral i‐trait Screening, Gene Identification, and Functional Validation for Genetic Dissection of Salt Tolerance in Cotton

Advanced Science, EarlyView.
An integrated phenomics–genomics framework captures dynamic salt‐stress responses in laboratory‐grown cotton seedlings through time‐series hyperspectral imaging and non‐destructive i‐trait extraction. Hierarchical screening identifies biologically relevant, heritable, and non‐redundant traits for high‐resolution GWAS, identifying GhST7.
Bowei Xu, Le Liu, Mengli Yu, Yuling Guo, Junli Ye, Jun Zhang, Rumeng Zhao, Jiajie Yang, Wanneng Yang, Yameng Xu, Liqiang Fan, Zuoren Yang   +11 more
wiley   +1 more source

A Novel Bioactive Component, Efoba, From Aged Garlic Targets CTSC to Suppress NET‐Driven Neuroinflammation and Ameliorate Secondary Brain Injury After Intracerebral Hemorrhage

Advanced Science, EarlyView.
Efoba, a novel bioactive component derived from aged garlic, confers neuroprotection against intracerebral hemorrhage. It acts on microglia to suppress CTSC release, inhibits NET‐mediated neural injury, and blocks pathological microglia‐neutrophil crosstalk. This study provides a highly promising lead compound for hemorrhagic‐stroke therapy.
Junjun Meng, Jianhua Wang, Tao Zhang, Xiaofan Fan, Jinxiu Guo, Shiyuan Zhao, Wenxue Sun, Pei Jiang   +7 more
wiley   +1 more source

Patents versus patients: ethical dilemmas in accessing lifesaving medicine in low- and middle-income countries. [PDF]

BMJ Glob Health
Odero BA, Mumbuluma E, Essack Z.
europepmc   +1 more source

Thyroid cancer and double-strand DNA break repair: The potential role of the MRN complex pathogenic variants. [PDF]

J Clin Transl Endocrinol
Gubbi S, Moorthy V, Grover A, Al-Souri D, Bin-Satter K, Veeraraghavan P, Cochran C, Klubo-Gwiezdzinska J.   +7 more
europepmc   +1 more source

Uncovering a feedback loop in glioblastoma that reinforces stemness and immunosuppression. [PDF]

J Clin Invest
Basakis P, Shih LK, Li J, Brat DJ.
europepmc   +1 more source