Results 41 to 50 of about 24,502 (300)

MISTIC: mutual information server to infer coevolution [PDF]

open access: yes, 2013
MISTIC (mutual information server to infer coevolution) is a web server for graphical representation of the information contained within a MSA (multiple sequence alignment) and a complete analysis tool for Mutual Information networks in protein families.
Teppa, Roxana Elin   +10 more
core   +1 more source

Parallel mutual information estimation for inferring gene regulatory networks on GPUs

open access: yesBMC Research Notes, 2011
Background Mutual information is a measure of similarity between two variables. It has been widely used in various application domains including computational biology, machine learning, statistics, image processing, and financial computing.
Liu Weiguo   +3 more
doaj   +1 more source

Amplification, Inference, and the Manifestation of Objective Classical Information

open access: yesEntropy, 2022
Our everyday reality is characterized by objective information—information that is selected and amplified by the environment that interacts with quantum systems.
Michael Zwolak
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Improved Prediction of Wind Speed using Machine Learning [PDF]

open access: yesEAI Endorsed Transactions on Energy Web, 2019
The prediction of wind speed plays a significant role in wind energy systems. An accurate prediction of wind speed is more important for wind energy systems, but it is difficult due to its uncertain nature.
Senthil Kumar P
doaj   +1 more source

GauSS-MI: Gaussian Splatting Shannon Mutual Information for Active 3D Reconstruction

open access: yesRobotics: Science and Systems XXI
This research tackles the challenge of real-time active view selection and uncertainty quantification on visual quality for active 3D reconstruction. Visual quality is a critical aspect of 3D reconstruction. Recent advancements such as Neural Radiance Fields (NeRF) and 3D Gaussian Splatting (3DGS) have notably enhanced the image rendering quality of ...
Yuhan Xie   +4 more
openaire   +2 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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