Results 61 to 70 of about 21,812 (251)

Bounds on the Excess Minimum Risk via Generalized Information Divergence Measures

open access: yesEntropy
Given finite-dimensional random vectors Y, X, and Z that form a Markov chain in that order (Y→X→Z), we derive the upper bounds on the excess minimum risk using generalized information divergence measures.
Ananya Omanwar   +2 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Reducing Uncertainty of Weak Supervised Signals via Mutual Information Techniques

open access: yesIEEE Access
Weakly supervised learning (WSL) refers to training models using imperfect or noisy labels, which can significantly reduce the costs associated with manual labeling.
Yichen Liu, Hanlin Feng, Xin Zhang
doaj   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Decoding MRI-informed brain age using mutual information

open access: yesInsights into Imaging
Objective We aimed to develop a standardized method to investigate the relationship between estimated brain age and regional morphometric features, meeting the criteria for simplicity, generalization, and intuitive interpretability.
Jing Li, Linda Chiu Wa Lam, Hanna Lu
doaj   +1 more source

Kolmogorov Capacity with Overlap

open access: yesEntropy
The notion of δ-mutual information between non-stochastic uncertain variables is introduced as a generalization of Nair’s non-stochastic information functional.
Anshuka Rangi, Massimo Franceschetti
doaj   +1 more source

A Minimax Mutual Information Scheme for Supervised Feature Extraction and Its Application to EEG-Based Brain-Computer Interfacing

open access: yesEURASIP Journal on Advances in Signal Processing, 2008
This paper presents a novel approach for efficient feature extraction using mutual information (MI). In terms of mutual information, the optimal feature extraction is creating a feature set from the data which jointly have the largest dependency on the ...
Farid Oveisi, Abbas Erfanian
doaj   +1 more source

The effect of anisotropy on holographic entanglement entropy and mutual information

open access: yesPhysics Letters B, 2019
We study the effect of anisotropy on holographic entanglement entropy (HEE) and holographic mutual information (MI) in the Q-lattice model, by exploring the HEE and MI for infinite strips along arbitrary directions.
Peng Liu, Chao Niu, Jian-Pin Wu
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

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