Results 51 to 60 of about 24,502 (300)

MI-PRUN: Optimize Large Language Model Pruning via Mutual Information

open access: yesICASSP 2026 - 2026 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP)
Large Language Models (LLMs) have become indispensable across various domains, but this comes at the cost of substantial computational and memory resources. Model pruning addresses this by removing redundant components from models. In particular, block pruning can achieve significant compression and inference acceleration.
Hao Zhang   +5 more
openaire   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Mutual Information as a General Measure of Structure in Interaction Networks

open access: yesEntropy, 2020
Entropy-based indices are long-established measures of biological diversity, nowadays used to gauge partitioning of diversity at different spatial scales.
Gilberto Corso   +2 more
doaj   +1 more source

A fair classifier using mutual information

open access: yes, 2020
As machine learning becomes prevalent in our daily lives involving a widening array of applications such as medicine, finance, job hiring and criminal justice, one morally legally motivated need for machine learning algorithms is to ensure fairness for ...
Hwang, Gyeongjo   +2 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Some Convex Functions Based Measures of Independence and Their Application to Strange Attractor Reconstruction

open access: yesEntropy, 2011
The classical information-theoretic measures such as the entropy and the mutual information (MI) are widely applicable to many areas in science and engineering. Csiszar generalized the entropy and the MI by using the convex functions.
Kazuyuki Aihara, Yang Chen
doaj   +1 more source

The Mutual Information Constellation

open access: yes, 2005
In this paper, we will explain the usefulness of what we call the mutual information (MI) constellation. We will show how it can be used both in analysis and in design of codes.
NILSSON, ANDERS   +5 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Entanglement wedge minimum cross-section in holographic massive gravity theory

open access: yesJournal of High Energy Physics, 2021
We study the entanglement wedge cross-section (EWCS) in holographic massive gravity theory, in which a first and second-order phase transition can occur.
Peng Liu   +3 more
doaj   +1 more source

An Integrated Approach to Air Passenger Index Prediction: Mutual Information Principle and Support Vector Regression (MI-Svr) Blended Model

open access: yes, 2020
Air passenger traffic prediction is crucial for the effective operation of civil aviation airports. Despite some progress in this field, the prediction accuracy and methods need further improvement. This paper proposes an integrated approach to the prediction of air passenger index as follows.
Honglin Xiong   +4 more
openaire   +3 more sources

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