Results 51 to 60 of about 21,812 (251)

Mutual Information as a General Measure of Structure in Interaction Networks

open access: yesEntropy, 2020
Entropy-based indices are long-established measures of biological diversity, nowadays used to gauge partitioning of diversity at different spatial scales.
Gilberto Corso   +2 more
doaj   +1 more source

An Integrated Approach to Air Passenger Index Prediction: Mutual Information Principle and Support Vector Regression (MI-Svr) Blended Model

open access: yes, 2020
Air passenger traffic prediction is crucial for the effective operation of civil aviation airports. Despite some progress in this field, the prediction accuracy and methods need further improvement. This paper proposes an integrated approach to the prediction of air passenger index as follows.
Honglin Xiong   +4 more
openaire   +3 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Entanglement wedge minimum cross-section in holographic massive gravity theory

open access: yesJournal of High Energy Physics, 2021
We study the entanglement wedge cross-section (EWCS) in holographic massive gravity theory, in which a first and second-order phase transition can occur.
Peng Liu   +3 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Detection of Respiration Movement Asymmetry Between the Left and Right Lungs Using Mutual Information and Transfer Entropy

open access: yesIEEE Access, 2018
Using diagnostic imaging, asymmetry in the mechanic of the left and right lungs has been discovered in unilateral lung disease. Unilateral lung disease might affect information interaction between two lungs, which is often neglected in the study of lung ...
Lianrong Zheng   +5 more
doaj   +1 more source

T-value and mutual information as measures of the association strength in Serbian language [PDF]

open access: yesPsihologija, 2006
Since the study of Meyer and Schvaneveldt (1971), a large number of researches have shown facilitation effect in cognitive processing of a given word when it is preceded by a semantically (i.e. associatively) related word.
Lisac Jelena, Milin Petar
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

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