Results 91 to 100 of about 3,416,169 (342)

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Real-valued feature selection for process approximation and prediction [PDF]

open access: yes, 2009
The selection of features for classification, clustering and approximation is an important task in pattern recognition, data mining and soft computing. For real-valued features, this contribution shows how feature selection for a high number of features ...
Brause, Rüdiger, Heister, Frank
core  

Access to Electronic Data for Criminal Investigations Purposes in the EU. CEPS Paper in liberty and security in Europe No. 2020-01, February 2020 [PDF]

open access: yes, 2020
Within the EU and across the Atlantic, investigation and prosecution of crime increasingly relies on the possibility to access, collect and transfer electronic information and personal data held by private companies across borders. Cross-border access to
Carrera, Sergio, Stefan, Marco
core  

Identity and identification in Azouz Begag’s Le Gone du Chaâba and Béni ou le paradis privé [PDF]

open access: yes, 2010
"Man is human only to the extent to which he tries to impose his existence on another man in order to be recognised by him [...] It is on that other being, on recognition by that other being, that his own human worth and reality depend." (Fanon 216-17 ...
Lewis, Jonathan
core   +3 more sources

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

THE EUROPEAN ARREST WARRANT. THE ENFORCEMENT OF THE EUROPEAN ARREST WARRANT IN THE UNITED KINGDOM. [PDF]

open access: yesChallenges of the Knowledge Society, 2019
The European arrest warrant has replaced the extradition procedure between the Member States of the European Union. Thus, by the introduction of the European arrest warrant, the administrative-judicial procedure was replaced by a purely judicial ...
Cosmin Iulian CRETU
doaj  

Transnational Criminal Proceedings, Witness Evidence and Confrontation: Lessons from the ECtHR’s Case Law

open access: yesUtrecht Law Review, 2013
A single European area of freedom, security and justice requires new models of judicial cooperation in criminal matters to be put in place in order to efficiently combat transnational organized crime.
Lorena Bachmaier Winter
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Intra-Ethnic Conflict and Ritual Morphing: A Psychoanalytic Study of Othering in Post-Holocaust Jewish Identity in Art Spiegelman’s Maus

open access: yesILN Journal: Indian Literary Narratives
The paper investigates Art Spiegelman’s Maus from a psychoanalytical perspective by drawing on the concepts of Thomas Ogden’s “analytic third” and Jessica Benjamin’s “intersubjectivity” to expose the trauma-driven intra-ethnic conflicts that lead to ...
Supriya M, Dr Wilfin John
doaj   +1 more source

“Knower” as an Ethical Concept: From Epistemic Agency to Mutual Recognition

open access: yesFeminist Philosophy Quarterly, 2018
Recent discussions in critical social epistemology have raised the idea that the concept “knower” is not only an epistemological concept but an ethical concept as well.
Matthew Congdon
semanticscholar   +1 more source

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