Results 81 to 90 of about 2,071,822 (293)
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Mutual recognition of COVID-19 vaccine to restore normal social activities and redistribute vaccines for the next stage of the pandemic. [PDF]
Sun C, Lowe S, Zhou Q, Nanola Uy JP.
europepmc +1 more source
Heterotropic regulation and negative homotropic cooperativity
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
EQA/PT scheme to improve the equivalence of enzymatic results between mutual recognition laboratories in Beijing. [PDF]
Tong Q, Zhang S, Zuo C.
europepmc +1 more source
Competency and Mutual Recognition [PDF]
In opening the 3rd International Conference on Pharmaceutical Competence Professor The Honourable Peter Baume spoke on the subject of the global health professional and, in his usual entertaining and provocative style, predicted the demise of tertiary education institutions as we presently know them and the rise of interactive learning through Inter‐or
openaire +1 more source
Mutual Information Based Gesture Recognition [PDF]
Proliferation of gestural interfaces necessitates the creation of robust gesture recognition systems. A novel technique using Mutual Information to classify gestures in a recognition system is presented. As this technique is based on well-known information theory metrics the underlying operation is not as complex as many other techniques which allows ...
Peter J. Harding +2 more
openaire +2 more sources
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia +9 more
wiley +1 more source
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa +4 more
wiley +1 more source
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page +4 more
wiley +1 more source

