Results 41 to 50 of about 93,435 (305)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
European Papers, 2017 (Series Information) European Papers - A Journal on Law and Integration, 2017 2(1), 141-157 | Article | (Table of Contents) I. Introduction: one or many faces of mutual trust in European integration? - II.
Luisa Marin
doaj +1 more source
Algorithms weighing lives and freedoms: The case of China’s health code
Smart Cities and Regional Development Journal, 2023 In response to the COVID-19 outbreak in the beginning of 2020, Chinese local governments created a software extension on existing mobile applications to monitor citizens’ movement and collect their health data.
Ina Virtosu, Chen Li
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Mutual Recognition, Unemployment and the Welfare State. ENEPRI Working Paper No. 13, September 2002 [PDF]
, 2002 Contents: 1. Introduction; 2. Rules and Regulations on Mutual Recognition in the European Union Markets; Mutual recognition, equivalence, competition and harmonisation; "Equal treatment" and "social dumping"; The minimum threshold; 3.
Schioppa, Padoa., Kostoris, Fiorella
core
, 1981 Trillmich F. Mutual mother-pup recognition in Galápagos fur seals and sea lions: cues used and functional significance. Behaviour. 1981;78(1):21-42.Field observations on Galápagos fur seals and sea lions indicate mutual recognition between mother and pup.
Trillmich, Fritz ; https://orcid.org/
core +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Mutual Recognition in Goods and Services: An Economic Perspective. ENEPRI Working Paper No. 16, March 2003 [PDF]
, 2003 Mutual recognition is a remarkable innovation facilitating economic intercourse across borders. In the EU's internal goods market it has been helpful in tackling or avoiding the remaining obstacles, namely, regulatory barriers between member states ...
Pelkmans, Jacques.
core
Holistic Integrative OncologyWith the continuous advancement of medical research, the number of multi-center clinical studies has been steadily increasing, bringing about significant challenges to ethical review.
Xiaolin Liu +5 more
doaj +1 more source