Results 51 to 60 of about 1,988,115 (295)

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Organizational Identity: An Ambiguous Concept in Practical Terms

open access: yesAdministrative Sciences, 2017
Albert and Whetten defined organizational identity (OI) as the central, distinctive and enduring characteristics of an organization. Scholars found OI to be a difficult construct to apply to organizations and, over time, they defined it from ...
Humaira Mujib
doaj   +1 more source

Legality, Double Criminality and Effectiveness in the European Arrest Warrant System: The Court of Justice in X

open access: yesEuropean Papers, 2020
(Series Information) European Papers - A Journal on Law and Integration, 2020 5(1), 461-467 | European Forum Insight of 28 May 2020 | (Table of Contents) I. Introduction. - II. Facts of the case and key legal issues. - III.
Lorenzo Grossio
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Mutual Recognition, Unemployment and the Welfare State. ENEPRI Working Paper No. 13, September 2002 [PDF]

open access: yes, 2002
Contents: 1. Introduction; 2. Rules and Regulations on Mutual Recognition in the European Union Markets; Mutual recognition, equivalence, competition and harmonisation; "Equal treatment" and "social dumping"; The minimum threshold; 3.
Schioppa, Padoa., Kostoris, Fiorella
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Regulation of procedural rights of suspect and accused person in the European Union acquis [PDF]

open access: yesStrani pravni život, 2020
Last two decades EU intensifies regulation of specific criminal law matters, both substantive and procedural. Although the EU was relay on Council of Europe and its instruments, adoption of Maastricht Treaty in 1992 and Amsterdam Treaty in 1997 reveal ...
Matić-Bošković Marina M.
doaj  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Mutual Recognition in Goods and Services: An Economic Perspective. ENEPRI Working Paper No. 16, March 2003 [PDF]

open access: yes, 2003
Mutual recognition is a remarkable innovation facilitating economic intercourse across borders. In the EU's internal goods market it has been helpful in tackling or avoiding the remaining obstacles, namely, regulatory barriers between member states ...
Pelkmans, Jacques.
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

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