Results 41 to 50 of about 85,417 (299)
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Innovating social connectedness for agricultural innovations in eastern Ethiopia
Agricultural innovations can be triggered by the social networks in which farmers have purposefully organized to support themselves. This paper, therefore, explores the values of social connectedness within locally established societies’ mutual support ...
Desalegn Yadeta Wedajo +1 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
An initial analysis of South African mutual fund expenses [PDF]
Includes bibliographical references (leaves 91-97).The following research aims to collect and collate a set of data relating to characteristics of mutual funds within the South African Mutual Fund Industry, with a specific focus on expenses. In addition,
Griffiths, James
core
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
(Series Information) European Papers - A Journal on Law and Integration, 2016 1(3), 1183-1193 | European Forum Insight of 5 January 2017 | (Table of Contents) I.
Stefano Montaldo
doaj +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
COMPARISON OF THE PERFORMANCE OF ISLAMIC MUTUAL FUNDS vs. ETHICAL AND CONVENTIONAL MUTUAL FUNDS [PDF]
Mutual funds are one of the key contributors to the globalisation of financial markets and one of the main sources of capital flows to emerging economies.
ALRASHIDI, FALEH,M,F,E
core
The EU model of international judicial cooperation in criminal matters, based on a high level of presumed mutual trust among Member States and on the principle of mutual recognition resulting therefrom, purports to go beyond traditional models of ...
Valsamis Mitsilegas
doaj +1 more source

