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We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
In wireless sensor networks, sensing information must be transmitted from sensor nodes to the base station by multiple hopping. Every sensor node is a sender and a relay node that forwards the sensing information that is sent by other nodes.
Chih-Hsueh Lin +5 more
doaj +1 more source
How to introduce yourself to patients [PDF]
Rationale and key points This article explores the process of introducing yourself to patients. This is an essential interaction because it forms the basis of the therapeutic nurse-patient relationship.
Guest, Mags
core +2 more sources
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Words Speak Louder Than Money [PDF]
Should one use words or money to foster trust of the other party if no means of enforcing trustworthiness are available? This paper reports an experiment studying the effectiveness of two types of mechanisms for promoting trust: a costly gift and a ...
Maroš Servátka +2 more
core +3 more sources
Koperasi Kredit Marsudi Mulyo, adheres to trust, honesty and cooperation as core values with respect to its establishment, membership, business management and conduct of social activities.
Rizki Emelia Sinuraya
doaj +1 more source
Molecular cancer prevention: Intercepting disease
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
(Series Information) European Papers - A Journal on Law and Integration, 2020 5(3), 1271-1288 | Article | (Table of Contents) I. Introduction. – II. La confiance mutuelle face aux violations des valeurs européennes. – II.1.
Tony Marguery
doaj +1 more source
Building Social Solidarity Through Mutual Trust
Cases C-156/21 and C-152/21 established that the implementation of solidarity is based on mutual trust. This reference is of significant relevance given that trust is essential when risky decisions are made in troubled times. In this context, this article analyses whether mutual trust could be decisive to tackle unexpected challenges, such as the ...
openaire +1 more source

