Results 51 to 60 of about 2,265,812 (340)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

The European Model of Judicial Cooperation in Criminal Matters: Towards Effectiveness based on Earned Trust

open access: yesRevista Brasileira de Direito Processual Penal, 2019
The EU model of international judicial cooperation in criminal matters, based on a high level of presumed mutual trust among Member States and on the principle of mutual recognition resulting therefrom, purports to go beyond traditional models of ...
Valsamis Mitsilegas
doaj   +1 more source

Trust in the digital world - the return of the kings of old [PDF]

open access: yes, 2008
Drawing principally on examples and literature from the Anglosphere, the author argues that the high salience given to "trust" and "trustworthiness" in recent scholarly literature, and which (notably in Putnam's work) attributes declining trust to a ...
Collins, Richard
core  

How friendship is defined matters for predicting intergroup attitudes: Shared activities and mutual trust with cross-ethnic peers during late childhood and early adolescence

open access: yesInternational Journal of Behavioral Development, 2018
We examined how two different definitions of cross-ethnic friendships, namely reciprocal peer nominations for shared activities and mutual trust, predict attitudes towards immigrant students among non-immigrant Swiss children and early adolescents (N ...
Jeanine Grütter, Linda R. Tropp
semanticscholar   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

No need to look, trust me! Mutual trust and distrust in the European arrest warrant system

open access: yesEuropean Law Open
No cooperative scheme in EU law has displayed bigger tensions between mutual trust and fundamental rights protection than the EAW system. Despite the requirement developed by the CJEU for national courts to trust each other and recognise each other’s ...
Matteo Bonelli   +1 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Patient Power and Empowerment: Mitigating Elements of Valuable Patient Participation in Healthcare Collaboratives

open access: yesBehavioral Sciences, 2023
During the last decade, the public healthcare sector has had to deal with increased competition, a growing influence of patient associations, and a necessity to deliver health services more efficiently and effectively.
Anja Minheere   +5 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Mutual trust method for forwarding information in wireless sensor networks using random secret pre-distribution

open access: yesAdvances in Mechanical Engineering, 2016
In wireless sensor networks, sensing information must be transmitted from sensor nodes to the base station by multiple hopping. Every sensor node is a sender and a relay node that forwards the sensing information that is sent by other nodes.
Chih-Hsueh Lin   +5 more
doaj   +1 more source

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