Results 81 to 90 of about 22,950 (304)

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

robertvsiii/niche-mutualism: Zenodo release

open access: yes, 2020
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Robert A Marsland III
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Asymptotic behavior of stochastic Gilpin-Ayala mutualism model with jumps

open access: yesElectronic Journal of Differential Equations, 2013
This article concerns the study of stochastic Gilpin-Ayala mutualism models with white noise and Poisson jumps. Firstly, an explicit solution for one-dimensional Gilpin-Ayala mutualism model with jumps is obtained and the asymptotic pathwise behavior ...
Xinhong Zhang, Ke Wang
doaj  

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

Biological Mutualism: A Scientific Survey

open access: yes, 2019
The phenomenon of mutualism—of mutually beneficial cooperation between organisms of different species—has come to a remarkable new prominence in the study of biology.

core   +2 more sources

De novo synthesis of short‐chain aldehydes and hydrocarbons secreted by the brown marmorated stink bug Halyomorpha halys

open access: yesFEBS Open Bio, EarlyView.
The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Stability of mutualisms in a lattice gas system of two species

open access: yesElectronic Journal of Differential Equations, 2015
This article considers mutualisms in a lattice gas system of two species. The species are mutualistic since each one can provide resources to the other. They are also competitive since they compete for empty sites on the same lattice.
Yuanshi Wang, Hong Wu
doaj  

Obligate mutualism in an extended consumer-resource framework

open access: yes, 2018
The development of a theory to underpin the obligate mutualist interactions that appear to be ubiquitous in nature has not proceeded at the same pace as the development of theory to support competition and predation.
Norbury, J, Cropp, RA
core  

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