Results 61 to 70 of about 145,873 (345)

Draft Genome Sequence of Photorhabdus temperata Strain Meg1, an Entomopathogenic Bacterium Isolated from Heterorhabditis megidis Nematodes [PDF]

, 2014
Photorhabdus temperata strain Meg1 is an entomopathogenic bacterium that forms a symbiotic association with Heterorhabditis nematodes. We report here a 4.9-Mbp draft genome sequence for P.
Abebe-Akele, Feseha, Abebe-Akele, Feseha, AbouZaied, Mohamed A., Badr, Usama M., Ghazal, Shimaa M., Hurst, Sheldon G., IV, Hussein, Mona A., Khalil, Kamal M., Morris, Krystalynne, Thomas, W. Kelley, Tisa, Louis S.   +10 more
core   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Skeleton-Based Mutually Assisted Interacted Object Localization and Human Action Recognition [PDF]

, 2021
Liang Xu, Cuiling Lan, Wenjun Zeng, Cewu Lu   +3 more
openalex   +1 more source

Roman roads: The hierarchical endosymbiosis of cognitive modules [PDF]

, 2009
Serial endosymbiosis theory provides a unifying paradigm for examining the interaction of cognitive modules at vastly different scales of biological, social, and cultural organization.
Wallace, Rodrick
core   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Does mutualism drive the invasion of two alien species? The case of Solenopsis invicta and Phenacoccus solenopsis.

PLoS ONE, 2012
Although mutualism between ants and honeydew-producing hemipterans has been extensively recognized in ecosystem biology, however few attempts to test the hypothesis that mutualism between two alien species leads to the facilitation of the invasion ...
Aiming Zhou, Yongyue Lu, Ling Zeng, Yijuan Xu, Guangwen Liang   +4 more
doaj   +1 more source

An Entomopathogenic Nematode by Any Other Name [PDF]

, 2012
Among the diversity of insect-parasitic nematodes, entomopathogenic nematodes (EPNs) are distinct, cooperating with insect-pathogenic bacteria to kill insect hosts.
Adams, Byron J., Chaston, John M., Ciche, Todd A., Dillman, Adler R., Goodrich-Blair, Heidi, Sternberg, Paul W., Stock, S. Patricia   +6 more
core   +3 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Emergence of structural and dynamical properties of ecological mutualistic networks

, 2013
Mutualistic networks are formed when the interactions between two classes of species are mutually beneficial. They are important examples of cooperation shaped by evolution.
A James, A Krishna, Amos Maritan, AR Ives, AR Thompson, C Campbell, E Thébault, F Zhang, Filippo Simini, J Bascompte, J Bascompte, J Guimarães, Jayanth R. Banavar, JM Montoya, JN Holland, KS McCann, LANovakM Twardochleb, M Almeida-Neto, M Pascual, MA Nowak, MA Nowak, MW Douglas, PP Staniczenko, PR Guimarães, RM May, S Allesina, S Allesina, S Saavedra, S Saavedra, Samir Suweis, SR Proulx, T Okuyama, U Bastolla, W Ulrich   +33 more
core   +1 more source

Draft Genome Sequence of Photorhabdus luminescens subsp. laumondii HP88, an Entomopathogenic Bacterium Isolated from Nematodes [PDF]

, 2016
Photorhabdus luminescens subsp. laumondii HP88 is an entomopathogenic bacterium that forms a symbiotic association with Heterorhabditis nematodes. We report here a 5.27-Mbp draft genome sequence for P. luminescens subsp.
Abebe-Akele, Feseha, Ghazal, Shimaa, Khalil, Kamal M., Morris, Krystalynne, Oshone, Rediet, Simpson, Stephen, Thomas, W. Kelley, Tisa, Louis S.   +7 more
core   +2 more sources