Results 51 to 60 of about 22,950 (304)

Indirect effects among biodiversity loss of mutualistic ecosystems

National Science Open, 2022
Drastic reduction in biodiversity has been a severe threat to ecosystems, which is exacerbated when losing few species leads to disastrous and even irreparable consequences.
Wang Guangwei, Liu Xueming, Chen Guanrong, Zhang Hai-Tao   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Research on mutualisms between native and non-native partners can contribute critical ecological insights

NeoBiota, 2015
Mutualisms are important structuring forces in ecological communities, influencing ecosystem functions, diversity, and evolutionary trajectories. New interactions, particularly between native and non-native species, are globally increasing in biotic ...
Clare E. Aslan, Benjamin A. Sikes, Keryn B. Gedan   +2 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

A unique resource mutualism between the giant Bornean pitcher plant, Nepenthes rajah, and members of a small mammal community.

PLoS ONE, 2011
The carnivorous pitcher plant genus Nepenthes grows in nutrient-deficient substrates and produce jug-shaped leaf organs (pitchers) that trap arthropods as a source of N and P.
Melinda Greenwood, Charles Clarke, Ch'ien C Lee, Ansou Gunsalam, Rohan H Clarke   +4 more
doaj   +1 more source

Short‐term apparent mutualism drives responses of aquatic prey to increasing productivity

, 2021
According to apparent competition theory, sharing a predator should cause indirect interactions among prey that can substantially influence food-web responses to environmental drivers.
Scharnweber, Kristin,, Chaguaceda, Fernando, Scharnweber, Kristin, Lars J. Tranvik, Tranvik, Lars,, Eklöv, Peter,, Eklöv, Peter, Chaguaceda, Fernando,, Kristin Scharnweber, Peter Eklöv, Tranvik, Lars, Fernando Chaguaceda, Erik Dalman   +12 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Coevolution and dependency influence resistance of mutualists to exploitation

Frontiers in Ecology and Evolution
A long-standing problem in the study of mutualism is to understand the effects of non-mutualistic community members that exploit the benefits of mutualism without offering commodities in exchange (i.e., ‘exploiters’).
Mayra C. Vidal, Renuka Agarwal, Kari A. Segraves   +2 more
doaj   +1 more source

Arthropod-Microbiota Integration: Its Importance for Ecosystem Conservation

Frontiers in Microbiology, 2021
Recent reports indicate that the health of our planet is getting worse and that genuine transformative changes are pressing. So far, efforts to ameliorate Earth’s ecosystem crises have been insufficient, as these often depart from current knowledge of ...
Constanza Schapheer, Constanza Schapheer, Roseli Pellens, Rosa Scherson   +3 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source