Using Cystine Knot Proteins as a Novel Approach to Retarget Oncolytic Measles Virus. [PDF]
, 2017 Modified measles virus (MV) has effective oncolytic activity preclinically and is currently being investigated in clinical trials for various types of cancer. We investigated the use of cystine knot proteins (CKPs) to direct MV activity.
Lal, Sangeet, Raffel, Corey
core +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
The Role of the Mass Collaboration in the Development of Society, Business and the State
Интеллект. Инновации. Инвестиции, 2019 The relevance of the topic under consideration is due to the growing popularity of the mass collaboration as a tool for activating the collective mind in order to increase the effectiveness of the organization’s activities and economic development ...
Yu.M. Polyakova
doaj +1 more source
Very Low Power Cockcroft-Walton Voltage Multiplier for RF Energy Harvesting Applications [PDF]
, 2019 A device was required that could harvest the electromagnetic energy present in ambient radio frequency (RF) signals. A part of this device must convert the AC RF signal received by the antenna into a DC signal that can be used in an embedded application.
Langdon, Trace
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MODULATION OF CALCIUM CHANNELS IN ARTERIAL SMOOTH-MUSCLE CELLS BY DIHYDROPYRIDINE ENANTIOMERS [PDF]
, 1993 The actions of the optical enantiomers of BAY K 8644 and Sandoz 202,791 were studied on barium inward currents recorded using the whole-cell configuration of the patch clamp technique from enzymatically isolated smooth muscle cells from the rabbit ear ...
Bolton, TB +3 more
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FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Endurance ou force dans le réentrainement à l'effort chez des patients atteints d'artériopathie oblitérante des membres inférieurs: revue de la littérature : travail de Bachelor [PDF]
, 2016 Introduction : Les modalités d’un réentrainement à l’effort chez les patients atteints d’artériopathie oblitérante des membres inférieurs (AOMI) sont décrites de façon précises et structurées concernant la marche, mais restent controversées pour le ...
Cuvelier, Virginie +2 more
core
A Solid State Transformer model for power flow calculations [PDF]
, 2017 This paper presents the implementation of a Solid State Transformer (SST) model in OpenDSS. The goal is to develop a SST model that could be useful for assessing the impact that the replacement of the conventional iron-and-copper transformer with the SST
Guerra Sánchez, Luis Gerardo +1 more
core +2 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Mass and angular momentum for the Kerr black hole in TEGR and STEGR
European Physical Journal C: Particles and FieldsWe study the energy–momentum characteristics of the rotating black hole–Kerr solution of general relativity in the teleparallel equivalent of general relativity (TEGR) and the symmetric teleparallel equivalent of general relativity (STEGR).
E. D. Emtsova +2 more
doaj +1 more source