Results 71 to 80 of about 1,568,516 (299)

Lexicographic pseudo MV-algebras

open access: yesJournal of Applied Logic, 2015
A lexicographic pseudo MV-algebra is an algebra that is isomorphic to an interval in the lexicographic product of a linear unital group with an arbitrary $\ell$-group. We present conditions when a pseudo MV-algebra is lexicographic. We show that a key condition is the existence of a lexicographic ideal, or equivalently, a case when the algebra can be ...
openaire   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Model Verification and the Likelihood Principle [PDF]

open access: yes, 2013
The likelihood principle (LP) is typically understood as a constraint on any measure of evidence arising from a statistical experiment. It is not sufficiently often noted, however, that the LP assumes that the probability model giving rise to a ...
Fletcher, Samuel C.
core   +1 more source

Microglia-derived microvesicles affect microglia phenotype in glioma [PDF]

open access: yes, 2019
Extracellular-released vesicles (EVs), such as microvesicles (MV) and exosomes (Exo) provide a new type of inter-cellular communication, directly transferring a ready to use box of information, consisting of proteins, lipids and nucleic acids.
Alfonso Grimaldi   +14 more
core   +5 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

"Der Glaube an..." als Thema im schulischen Unterricht: ein "Ja, aber" [PDF]

open access: yes, 2015
Ob die Frage nach dem "Glauben an die Existenz von..." einen Platz im Unterricht der öffentlichen Schule hat, kann aus religions- wissenschaftlicher und rechtlicher Sicht nur mit Einschränkungen bejaht werden.
Bleisch, Petra
core  

Missing observation analysis for matrix-variate time series data [PDF]

open access: yes, 2008
Bayesian inference is developed for matrix-variate dynamic linear models (MV-DLMs), in order to allow missing observation analysis, of any sub-vector or sub-matrix of the observation time series matrix.
Triantafyllopoulos, K.
core   +3 more sources

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

open access: yes
Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja   +8 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The renormalization group for correlated scales: one-stage versus two-stage running [PDF]

open access: yes, 2000
Nonrelativistic bound states have two low energy scales, a soft scale mu_S of order mv and an ultrasoft scale mu_U of order mv^2. In two-stage running, the soft and ultrasoft scales are lowered from m to mv, and then the ultrasoft scale is lowered from ...
Aneesh V. Manohar   +19 more
core   +2 more sources

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