Results 41 to 50 of about 26,170 (206)

Disgorging the MVB

open access: yesThe Journal of Cell Biology, 2001
The multivesicular body (MVB), a cluster of vesicles surrounded by a limiting membrane, is a ubiquitous but poorly understood structure in eukaryotic cells. On page 53,Kleijmeer et al. present the first evidence that the MVB can be used as a temporary storage depot for membranes and membrane proteins, which can then be deployed rapidly to the surface ...
openaire   +2 more sources

No ESCRT to the Melanosome: MVB Sorting without Ubiquitin [PDF]

open access: yesDevelopmental Cell, 2006
Multivesicular bodies (MVBs) are critical for a variety of cellular functions ranging from lysosomal degradation to the budding of HIV. To date, delivery into MVBs has been dependent on the ESCRT machinery. However, analysis of a melanosomal protein has uncovered an alternative pathway for MVB sorting.
openaire   +2 more sources

Weighted Co-SVM for Image Retrieval with MVB Strategy [PDF]

open access: yes2007 IEEE International Conference on Image Processing, 2007
In relevance feedback, active learning is often used to alleviate the burden of labeling by selecting only the most informative data. Traditional data selection strategies often choose the data closest to the current classification boundary to label, which are in fact not informative enough.
Xiaoyu Zhang   +3 more
openaire   +1 more source

Nano-Biofungicides and Bio-Nanofungicides: State of the Art of Innovative Tools for Controlling Resistant Phytopathogens

open access: yesBiophysica
Fungal diseases represent a significant threat to global agriculture, leading to substantial crop losses and endangering food security worldwide. Conventional chemical fungicides, while effective, are increasingly criticized for their detrimental ...
José Sebastian Dávila Costa   +1 more
doaj   +1 more source

Upregulation of the ESCRT pathway and multivesicular bodies accelerates degradation of proteins associated with neurodegeneration

open access: yesAutophagy Reports, 2023
Many neurodegenerative diseases, including Huntington’s disease (HD) and Alzheimer’s disease (AD), occur due to an accumulation of aggregation-prone proteins, which results in neuronal death.
Ron Benyair   +16 more
doaj   +1 more source

Radiation of an electric charge in the field of a magnetic monopole [PDF]

open access: yes, 2009
We consider the radiation of photons from quarks scattering on color-magnetic monopoles in the Quark-Gluon Plasma. We consider a temperature regime $T\gsim2T_c$, where monopoles can be considered as static, rare objects embedded into matter consisting ...
B. Berestetskii   +8 more
core   +1 more source

Masses of vector bosons in two-color dense QCD based on the hidden local symmetry

open access: yes, 2010
We construct a low energy effective Lagrangian for the two-color QCD including the "vector" bosons (mesons with J^P=1^- and diquark baryons with J^P=1^+) in addition to the pseudo Nambu-Goldstone bosons with a degenerate mass M_\pi (mesons with J^P=0 ...
Harada, Masayasu   +2 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

CHARACTERIZATION OF THE UBIQUITIN LIGASE, UBE4B, IN ENDOCYTIC TRAFFICKING [PDF]

open access: yes, 2017
Endocytosis is a process by which cells internalize membrane proteins to remove them from the plasma membrane, allowing cells to regulate the cell surface expression of transmembrane proteins.
Sirisaengtaksin, Natalie   +1 more
core   +1 more source

Retrograde trafficking of Argonaute 2 acts as a rate-limiting step for de novo miRNP formation on endoplasmic reticulum–attached polysomes in mammalian cells [PDF]

open access: yes, 2020
microRNAs are short regulatory RNAs in metazoan cells. Regulation of miRNA activity and abundance is evident in human cells where availability of target messages can influence miRNA biogenesis by augmenting the Dicer1-dependent processing of precursors ...
Barman, Bahnisikha   +4 more
core  

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