Results 51 to 60 of about 26,170 (206)

Direct N-body Modelling of Stellar Populations: Blue Stragglers in M67 [PDF]

open access: yes, 2000
We present a state-of-the-art N-body code which includes a detailed treatment of stellar and binary evolution as well as the cluster dynamics. This code is ideal for investigating all aspects relating to the evolution of star clusters and their stellar ...
Aarseth, Sverre J.   +3 more
core   +3 more sources

s‐Orbital Mediated Metavalent Bonding Enables State‐Of‐The‐Art n‐Type AgBiSe2 Thermoelectrics

open access: yesAdvanced Functional Materials, EarlyView.
Metavalent bonding (MVB) underpins the exceptional property portfolio of chalcogenides. Typical MVB solids are mainly found in p‐bonded systems. This work reveals that MVB can also be formed with s‐p orbital interactions upon forming a single‐electron σ‐bond, as exemplified in AgBiSe2.
Binrong Huang   +13 more
wiley   +1 more source

Principal Component Analysis of Weak Lensing Surveys

open access: yes, 2005
We study degeneracies between cosmological parameters and measurement errors from cosmic shear surveys using a principal component analysis of the Fisher matrix.
Anderson   +55 more
core   +4 more sources

Centrosomal P4.1-associated protein (CPAP) positively regulates endocytic vesicular transport and lysosome targeting of EGFR

open access: yesScientific Reports, 2021
Centrosomal P4.1-associated protein (CPAP) plays a critical role in restricting the centriole length in human cells. Here, we report a novel, positive regulatory influence for CPAP on endocytic vesicular transport (EVT) and lysosome targeting of ...
Radhika Gudi   +2 more
doaj   +1 more source

Structural and Functional Characterization of EXPO‐Derived Extracellular Vesicles in Plants

open access: yesAdvanced Science, EarlyView.
In this study, 3D electron tomography (ET), cryo‐ET, and immunogold transmission electron microscopy (TEM) are employed to characterize plant extracellular vesicles (EVs) under physiological conditions. EVs are classified into three distinct categories according to their size, content, and molecular‐marker profiles. Furthermore, Exo70E2‐positive medium
Jiayang Gao   +12 more
wiley   +1 more source

Clostridium perfringens epsilon toxin induces blood brain barrier permeability via caveolae-dependent transcytosis and requires expression of MAL. [PDF]

open access: yes, 2019
Clostridium perfringens epsilon toxin (ETX) is responsible for causing the economically devastating disease, enterotoxaemia, in livestock. It is well accepted that ETX causes blood brain barrier (BBB) permeability, however the mechanisms involved in this
Dobrow, Sebastian   +7 more
core   +1 more source

HRS Degradation‐Induced Nicotinamide Deficiency in Placental Extracellular Vesicles Triggers Preeclampsia by Disrupting Maternal‐Fetal Immune Homeostasis

open access: yesAdvanced Science, EarlyView.
This study shows that lower NAM levels in PE‐derived pEVs correlate with disease severity. NAM‐deficient pEVs reduce Th1 and Th17 inhibition, leading to PE‐like symptoms. NAM in pEVs inhibits Th1 via SIRT1 and Th17 via macrophages. Reduced NAM in PE‐EVs is due to decreased HRS expression in trophoblasts, resulting from elevated HSP27.
Haiyi Fei   +10 more
wiley   +1 more source

ALIX binds a YPX(3)L motif of the GPCR PAR1 and mediates ubiquitin-independent ESCRT-III/MVB sorting. [PDF]

open access: yes, 2012
The sorting of signaling receptors to lysosomes is an essential regulatory process in mammalian cells. During degradation, receptors are modified with ubiquitin and sorted by endosomal sorting complex required for transport (ESCRT)-0, -I, -II, and -III ...
Chen, Buxin   +7 more
core   +3 more sources

Tethering of Multi-Vesicular Bodies and the Tonoplast to the Plasma Membrane in Plants

open access: yesFrontiers in Plant Science, 2019
Tethering of the plasma membrane (PM) and many organelles to the endoplasmic reticulum (ER) for communication and lipid exchange has been widely reported. However, despite growing interest in multi-vesicular bodies (MVBs) as possible sources of exosomes,
Kai Tao   +7 more
doaj   +1 more source

Carbapenem-resistant Enterobacterales susceptibility patterns to new antimicrobials: A single-center analysis

open access: yesAntimicrobial Stewardship & Healthcare Epidemiology, 2023
Background: Multidrug-resistant bacteria are of high concern, and empiric antimicrobial choice for infections caused by these pathogens, while awaiting susceptibilities, is increasingly encountered.
Miranda Monk   +3 more
doaj   +1 more source

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