Results 151 to 160 of about 47,298 (270)
Complement Inhibition in the Clinic: Are We Doing Enough to Protect Patients From Infection?
Excessive complement activation is implicated in a broad range of diseases. Therapeutic approaches targeting the complement cascade, from pathway‐selective inhibition to terminal blockade, can effectively control disease activity. However, increasing degrees of complement inhibition are associated with a heightened susceptibility to bacterial, viral ...
Serena Bettoni +4 more
wiley +1 more source
Myasthenia gravis is a disorder of neuromuscular transmission resulting from binding of autoantibodies to various components of the neuromuscular junction.
Matthew J. Thurtell
core
ABSTRACT With increased survival due to enzyme replacement therapy, children with classic infantile Pompe disease tend to develop a clinical phenotype with pronounced distal muscle weakness, while late‐onset patients typically exhibit proximal muscle weakness.
Jan J. A. van den Dorpel +7 more
wiley +1 more source
ABSTRACT Mitochondrial carbonic anhydrase VA (CA‐VA) deficiency is a rare inherited metabolic disorder caused by biallelic variants of the CA5A gene. It presents with hyperammonemia, lactic acidosis, and ketonuria, with or without hypoglycemia. We report the long‐term follow‐up of the first two reported cases of CA‐VA deficiency: a 16‐year‐old female ...
Shaymaa Shurrab +5 more
wiley +1 more source
Myasthenia Gravis: Recent Developments
To: 1. Describe the potential mechanisms for preferential involvement of ocular muscles by myasthenia gravis; 2. Discuss risks and benefits of corticosteroid use for treatment of ocular myasthenia; 3. Appropriately use edrophonium, serum autoantibody and
Henry J. Kaminski, MD
core
ABSTRACT Introduction/Aims Physical activity and sleep influence fatigue in myasthenia gravis (MG), and digital health technologies (DHT) enable objective monitoring of these behaviors in daily life. Using this approach, we evaluated whether a lifestyle intervention targeting physical activity or sleep hygiene could reduce fatigue in MG.
Maja Norling +9 more
wiley +1 more source
Telitacicept in refractory juvenile generalized myasthenia gravis: a case report and collective analysis. [PDF]
Sun Y, Liu G, Zhang H, Ma K.
europepmc +1 more source
Among thyroid transcription factor‐1 (TTF‐1) negative non‐squamous (non‐sq) NSCLC patients, platinum and pemetrexed plus pembrolizumab showed comparable and preferable efficacy in terms of progression‐free survival and overall survival to that observed in TTF‐1‐positive patients.
Ryohei Kamada +10 more
wiley +1 more source
Clinical effectiveness of efgartigimod in a broad population of patients with generalized myasthenia gravis: subgroup analyses from a randomized, double‑blind, placebo‑controlled, phase 3 trial (ADAPT). [PDF]
Howard JF +10 more
europepmc +1 more source

