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Journal of Gerontological Nursing, 2013
<p>Myasthenia gravis (MG) is a chronic neuromuscular disorder characterized by fluctuating skeletal muscle weakness and fatigue. This rare autoimmune condition can present a diagnostic challenge for the advanced practice nurse (APN). Because of its low incidence in clinical practice and frequently unrecognized symptoms, a delay of 1 to 2 years ...
Julie A, Koch +2 more
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<p>Myasthenia gravis (MG) is a chronic neuromuscular disorder characterized by fluctuating skeletal muscle weakness and fatigue. This rare autoimmune condition can present a diagnostic challenge for the advanced practice nurse (APN). Because of its low incidence in clinical practice and frequently unrecognized symptoms, a delay of 1 to 2 years ...
Julie A, Koch +2 more
openaire +3 more sources
Disease-a-Month, 1997
Adult-onset myasthenia gravis is an acquired autoimmune disorder of neuromuscular transmission in which acetylcholine receptor antibodies attack the postsynaptic membrane of the neuromuscular junction. Although the cause of this disease is unknown, the role of immune responses in its pathogenesis is well established.
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Adult-onset myasthenia gravis is an acquired autoimmune disorder of neuromuscular transmission in which acetylcholine receptor antibodies attack the postsynaptic membrane of the neuromuscular junction. Although the cause of this disease is unknown, the role of immune responses in its pathogenesis is well established.
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Pediatric Annals, 1989
Twelve children with myasthenic symptoms were seen over a period of 6 years. The age of onset of symptoms ranged from 6 months to 9 years. On followup for a mean period of 4.25 years, (longest followup was 9 years) five children went into complete remission of symptoms after treatment with prostigmine; three children responded to prostigmine and ...
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Twelve children with myasthenic symptoms were seen over a period of 6 years. The age of onset of symptoms ranged from 6 months to 9 years. On followup for a mean period of 4.25 years, (longest followup was 9 years) five children went into complete remission of symptoms after treatment with prostigmine; three children responded to prostigmine and ...
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Current Treatment Options in Neurology, 2010
Treatment of patients with acquired (autoimmune) myasthenia gravis should rely on evidence-based therapeutic choices, taking into account the individual's needs according to disease severity (mild to severe), extent (ocular or generalized), comorbidities (including other autoimmune diseases, infections, thymoma, and pregnancy), age, iatrogenic factors (
Agnes, Jani-Acsadi, Robert P, Lisak
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Treatment of patients with acquired (autoimmune) myasthenia gravis should rely on evidence-based therapeutic choices, taking into account the individual's needs according to disease severity (mild to severe), extent (ocular or generalized), comorbidities (including other autoimmune diseases, infections, thymoma, and pregnancy), age, iatrogenic factors (
Agnes, Jani-Acsadi, Robert P, Lisak
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Veterinary Clinics of North America: Small Animal Practice, 1979
Myasthenia gravis is characterized by muscle weakness, which is alleviated by rest and by anticholinesterase drugs. There are two forms of the disease in the dog, acquired and congenital. The acquired form occurs either in young adults, or in older animals that have developed mediastinal tumors. Clinically, there is weakness of the muscles of the limbs,
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Myasthenia gravis is characterized by muscle weakness, which is alleviated by rest and by anticholinesterase drugs. There are two forms of the disease in the dog, acquired and congenital. The acquired form occurs either in young adults, or in older animals that have developed mediastinal tumors. Clinically, there is weakness of the muscles of the limbs,
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The Neurologist, 2002
In myasthenia gravis (MG), the prototypic autoimmune disease, antibodies against acetylcholine receptors impair neuromuscular transmission and produce weakness. Although recognized for several hundred years, it has only been over the last three decades that effective treatments have become available for MG.This review summarizes the principles of ...
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In myasthenia gravis (MG), the prototypic autoimmune disease, antibodies against acetylcholine receptors impair neuromuscular transmission and produce weakness. Although recognized for several hundred years, it has only been over the last three decades that effective treatments have become available for MG.This review summarizes the principles of ...
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Current Opinion in Immunology, 1993
The cause of the myasthenics' pathogenic autoantibody response against the muscle acetylcholine receptor is an intriguing puzzle involving the thymus and its epithelial tumours, and possibly a variety of cross-reacting epitopes. Another fascinating challenge is to find ways of selectively inhibiting this response in the patients.
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The cause of the myasthenics' pathogenic autoantibody response against the muscle acetylcholine receptor is an intriguing puzzle involving the thymus and its epithelial tumours, and possibly a variety of cross-reacting epitopes. Another fascinating challenge is to find ways of selectively inhibiting this response in the patients.
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Myasthenia Gravis: Epidemiology, Pathophysiology and Clinical Manifestations
Journal of Clinical Medicine, 2021Laura Dresser +2 more
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