Results 31 to 40 of about 91,972 (285)
Long-term efficacy and safety of eculizumab in Japanese patients with generalized myasthenia gravis : a subgroup analysis of the REGAIN open-label extension study [PDF]
, 2019 The terminal complement inhibitor eculizumab was shown to improve myasthenia gravis-related symptoms in the 26-week, phase 3, randomized, double-blind, placebo-controlled REGAIN study (NCT01997229).
De Bleecker, Jan +12 more
core +1 more source
Myasthenia Gravis Associated With SARS-CoV-2 Infection
Annals of Internal Medicine, 2020 Myasthenia Gravis Associated With SARS-CoV-2 Infection Background: Some patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have neurologic symptoms (1–3).
D. Restivo +3 more
semanticscholar +1 more source
Autoimmunity, 2004 Myasthenia gravis is a disorder of neuromuscular transmission, manifest by variable weakness of skeletal muscle. The disorder has a range of therapies that differ with respect to efficacy, timing, and side effects. The physician treating myasthenia gravis must be well versed in understanding the evidence basis for using these agents, as well as the ...
Vincent, A, Rothwell, P
openaire +6 more sources
A Case of COVID-19 Vaccine Causing a Myasthenia Gravis Crisis
Cureus, 2021 Myasthenia gravis is a rare disease of the neuromuscular junction subsequently affecting the bulbar, respiratory, and extremity skeletal muscles. It is an autoimmune disease in which antibodies target the acetylcholine receptor (AChR), preventing ...
A. Tagliaferri +3 more
semanticscholar +1 more source
Outcomes after major surgery in patients with myasthenia gravis: A nationwide matched cohort study. [PDF]
PLoS ONE, 2017 To validate the comprehensive features of adverse outcomes after surgery for patients with myasthenia gravis.Using reimbursement claims from Taiwan's National Health Insurance Research Database, we analyzed 2290 patients who received major surgery ...
Yi-Wen Chang +7 more
doaj +1 more source
Zhongliu Fangzhi Yanjiu, 2021 Objective To evaluate the correlation of prognostic nutritional index(PNI) with overall survival of postoperative patients with thymoma. Methods The clinical and pathological data of 173 postoperative patients with thymoma were analyzed retrospectively ...
WANG Yan +3 more
doaj +1 more source
JAMA Neurology, 2020 Key Points Question What are the clinical effects of zilucoplan, a subcutaneously self-administered macrocyclic peptide inhibitor of complement component 5, in a broad population of patients with moderate to severe acetylcholine receptor autoantibody ...
J. Howard +77 more
semanticscholar +1 more source
A Case of COVID-19 Vaccine Associated New Diagnosis Myasthenia Gravis
Journal of Primary Care & Community Health, 2021 An 82-year-old man presented with intermittent episodes of slurred speech during his evening meals after receiving the BNT162b2 COVID-19 vaccine. Thorough evaluation was conducted including lab work and EMG confirming a new diagnosis of late-onset ...
Augustine Chavez, Charlotte A. Pougnier
semanticscholar +1 more source
Synaptic plasticity and cognitive function are disrupted in the absence of Lrp4. [PDF]
, 2014 Lrp4, the muscle receptor for neuronal Agrin, is expressed in the hippocampus and areas involved in cognition. The function of Lrp4 in the brain, however, is unknown, as Lrp4-/- mice fail to form neuromuscular synapses and die at birth.
Burden, Steven J +2 more
core +1 more source
International Consensus Guidance for Management of Myasthenia Gravis
Neurology, 2020 Objective To update the 2016 formal consensus-based guidance for the management of myasthenia gravis (MG) based on the latest evidence in the literature.
P. Narayanaswami +16 more
semanticscholar +1 more source