Results 41 to 50 of about 46,950 (237)

Eculizumab as a promising treatment in thymoma-associated myasthenia gravis [PDF]

, 2020
Myasthenia gravis is a chronic autoimmune disorder caused by antibodies directed against the neuromuscular junction. Some patients may have an associated thymoma, which confers a worse prognosis.
Alberti, Maria Antonia, Casasnovas Pons, Carlos, Díez, Laura, Homedes, Christian, Nedkova, Velina, Vélez Santamaria, Valentina   +5 more
core   +1 more source

Clinical characteristics of myasthenia gravis (MG) patients developing other autoimmune diseases after thymectomy from one single center cohort

Thoracic Cancer, Volume 14, Issue 2, Page 135-142, January 2023., 2023
A total of 445 myasthenia gravis (MG) patients in which thymectomy was performed were included in this cohort. Nineteen patients (4.3%) developed a new autoimmune disease (AD) after thymectomy. The most common types of new onset ADs after thymectomy were Hashimoto's thyroiditis and rheumatoid arthritis (RA), which were different from those before ...
Wenxin Tian, Jing He, Hanbo Yu, Yaoguang Sun, Qingjun Wu, Peng Jiao, Chao Ma, Chuan Huang, Donghang Li, Hongfeng Tong   +9 more
wiley   +1 more source

Clinical predictors for the prognosis of myasthenia gravis

BMC Neurology, 2017
Background Clinical predictors for myasthenia gravis relapse and ocular myasthenia gravis secondary generalization during the first two years after disease onset remain incompletely identified.
Lili Wang, Yun Zhang, Maolin He
doaj   +1 more source

Antibodies to acetylcholine receptor in parous women with myasthenia: evidence for immunization by fetal antigen [PDF]

, 2002
The weakness in myasthenia gravis (MG) is mediated by autoantibodies against adult muscle acetylcholine receptors (AChR) at the neuromuscular junction; most of these antibodies also bind to fetal AChR, which is present in the thymus.
Beeson, D., Ledwidge, S., Matthews, I., Sims, G., Stott, D.I., Vincent, A., Wilcox, N.   +6 more
core   +1 more source

Prognostic factors and genetic markers in thymic epithelial tumors: A narrative review

Thoracic Cancer, Volume 13, Issue 23, Page 3242-3249, December 2022., 2022
The aim of this review article is to discuss the different prognostic factors and genetic markers of TET and to point out discrepancies and similarities among the available literature (concerning prognostic factors) and more importantly to demonstrate the genetic pathways that could be the basis of a development of new targeted therapies.
Apostolos C. Agrafiotis, Vasiliki Siozopoulou, Jeroen M. H. Hendriks, Patrick Pauwels, Senada Koljenovic, Paul E. Van Schil   +5 more
wiley   +1 more source

Impact of SARS-CoV-2 infection on patients with myasthenia gravis: a retrospective study in a Chinese population

Frontiers in Neurology
Background and purposeMyasthenia gravis (MG) is characterized by fluctuating muscle weakness due to immune-mediated damage to acetylcholine receptors. Viral infections can exacerbate symptoms of muscle weakness, and the clinical status of patients with ...
Peng Liu, Peng Liu, Mengna Li, Liqing Li, Wenli Jia, Huimin Dong, Guoyan Qi, Guoyan Qi, Guoyan Qi   +8 more
doaj   +1 more source

Concentric Needle Jitter in 97 Myasthenia Gravis Patients

Frontiers in Neurology, 2020
Objectives: To estimate the jitter parameters (single-fiber electromyography) in myasthenia gravis patients mostly by electrical activation in Frontalis, Orbicularis Oculi, and Extensor Digitorum muscles using a concentric needle electrode.Methods ...
João Aris Kouyoumdjian, Gabriel Pina Paiva, Erik Stålberg   +2 more
doaj   +1 more source

Black Holes with Weyl Charge and Non-Riemannian Waves [PDF]

Class.Quant.Grav.12:2587-2605,1995, 1995
A simple modification to Einstein's theory of gravity in terms of a non-Riemannian connection is examined. A new tensor-variational approach yields field equations that possess a covariance similar to the gauge covariance of electromagnetism. These equations are shown to possess solutions analogous to those found in the Einstein-Maxwell system.
arxiv   +1 more source

Survivin as a potential mediator to support autoreactive cell survival in myasthenia gravis: a human and animal model study. [PDF]

PLoS ONE, 2014
The mechanisms that underlie the development and maintenance of autoimmunity in myasthenia gravis are poorly understood. In this investigation, we evaluate the role of survivin, a member of the inhibitor of apoptosis protein family, in humans and in two ...
Linda L Kusner, Michael J Ciesielski, Alexander Marx, Henry J Kaminski, Robert A Fenstermaker   +4 more
doaj   +1 more source

Intrapericardial Thymoma Presented as Pericardial Tamponade with Post-Operative Myasthenia Gravis

Medicina, 2022
Background: Thymoma is an epithelial mass arising from the thymus. Most thymomas are located in the anterior mediastinum. Ectopic intrapericardial thymoma is very unusual; to date, only eight cases of pericardial thymoma have been reported. Among thymoma
Yueh-Hsun Tsai, Kai-Hsiung Ko, Hao Yen, Tsai-Wang Huang   +3 more
doaj   +1 more source