Results 41 to 50 of about 16,650 (226)
We report on a co-occurrence case of ocular myasthenia gravis with exacerbation leading to myasthenic crisis in addition to pharyngeal-cervical-brachial variant of Guillain–Barré syndrome in a patient with severe oropharyngeal dysphagia and acute ...
Stacey Ho, Antonio Liu
doaj +1 more source
ABSTRACT Introduction/Aims Myasthenia gravis (MG) is associated with thymic neoplasms. However, an increased prevalence of extrathymic neoplasms has also been reported. This study aimed to evaluate the rates of malignancy in MG patients while accounting for risk factors such as disease characteristics and immunomodulatory treatments.
Keshet Pardo +13 more
wiley +1 more source
Objective To evaluate the risk of myasthenia gravis (MG) associated with immune checkpoint inhibitors (ICI). Methods Adverse event (AE) reports related to MG, myasthenic syndrome, and MG crisis for durvalumab, atezolizumab, pembrolizumab, nivolumab ...
Qingli Kong +4 more
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ABSTRACT This review examines the emerging application of chimeric antigen receptor (CAR) T‐cell therapy in myasthenia gravis (MG), with emphasis on safety, efficacy signals, and future therapeutic potential in treatment‐refractory disease. A comprehensive literature search was conducted across PubMed, medRxiv, bioRxiv, and Google Scholar for studies ...
Tobias Hegelmaier +7 more
wiley +1 more source
Lambert-Eaton Syndrome in Children
Investigators from Boston Children's Hospital; the Lahey Clinic, Burlington, MA; and Ohio State University, report 3 children presenting between ages 9 and 10 years with proximal lower extremity weakness with areflexia and low-amplitude compound muscle ...
J Gordon Millichap, John J Millichap
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Structural Lung Disease in Children and Adolescents With Severe Neurological Disorders
ABSTRACT Background and Objective Children with severe neurological disorders are at risk of secondary respiratory morbidity due to impaired airway clearance and dysphagia, but systematic data on structural lung changes remain scarce. Methods We retrospectively analyzed all clinically indicated chest CT examinations at a tertiary care center (2015–2025)
Daniel A. F. Bernard +15 more
wiley +1 more source
Congenital Myasthenic Syndrome and AChR Mutation
A 20-year-old woman from a consanguineous Moroccan marriage, with progressive muscle weakness noted from 2 years of age and evaluated at the University of Bonn, Germany, was found to have congenital myasthenic syndrome (CMS) due to homozygosity of the ...
J Gordon Millichap
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In a cohort of 2043 patients treated with immune checkpoint inhibitors (ICI), severe neurological immune‐related adverse events (n‐irAEs) occurred in 0.5% of cases. These events predominantly involved the peripheral nervous system (PNS) and showed variable onset.
Anna Grisold +10 more
wiley +1 more source
Adverse Drug Reaction Study of Botulinum Toxin‐A in the Real World
ABSTRACT Background Despite the increasing use of botulinum toxin type A (BoNT‐A) in aesthetic and therapeutic applications, its real‐world adverse drug reaction (ADR) profile remains incompletely characterized. Current evidence relies largely on small‐scale clinical observations rather than large, systematic analyses.
Jiaxu Gu +9 more
wiley +1 more source
Background Congenital myasthenic syndromes caused by mutations in the COL13A1 gene are very rare and have a phenotype described as severe. We present the first case of congenital myasthenic syndrome described in Algeria and the Maghreb with a new ...
Mohamed Islam Kediha +4 more
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